Prognostic Impact of Combined Contrast-Induced Acute Kidney Injury and Hypoxic Liver Injury in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Results from INTERSTELLAR Registry
DC Field | Value | Language |
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dc.contributor.author | Park, Sang-Don | - |
dc.contributor.author | Moon, Jeonggeun | - |
dc.contributor.author | Kwon, Sung Woo | - |
dc.contributor.author | Suh, Young Ju | - |
dc.contributor.author | Kim, Tae-Hoon | - |
dc.contributor.author | Jang, Ho-Jun | - |
dc.contributor.author | Suh, Jon | - |
dc.contributor.author | Park, Hyun Woo | - |
dc.contributor.author | Oh, Pyung Chun | - |
dc.contributor.author | Shin, Sung-Hee | - |
dc.contributor.author | Woo, Seong-Il | - |
dc.contributor.author | Kim, Dae-Hyeok | - |
dc.contributor.author | Kwan, Jun | - |
dc.contributor.author | Kang, WoongChol | - |
dc.date.available | 2020-02-28T01:42:52Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2016-07-14 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8103 | - |
dc.description.abstract | Background Besides contrast-induced acute kidney injury(CI-AKI), adscititious vital organ damage such as hypoxic liver injury(HLI) may affect the survival in patients with ST-elevation myocardial infarction (STEMI). We sought to evaluate the prognostic impact of CI-AKI and HLI in STEMI patients who underwent primary percutaneous coronary intervention (PCI). Methods A total of 668 consecutive patients (77.2% male, mean age 61.3 +/- 13.3 years) from the INTERSTELLAR STEMI registry who underwent primary PCI were analyzed. CI-AKI was defined as an increase of >= 0.5 mg/dL in serum creatinine level or 25% relative increase, within 48h after the index procedure. HLI was defined as >= 2-fold increase in serum aspartate transaminase above the upper normal limit on admission. Patients were divided into four groups according to their CI-AKI and HLI states. Major adverse cardiovascular and cerebrovascular events (MACCE) defined as a composite of all-cause mortality, non-fatal MI, non-fatal stroke, ischemia-driven target lesion revascularization and target vessel revascularization were recorded. Results Over a mean follow-up period of 2.2 +/- 1.6 years, 94 MACCEs occurred with an event rate of 14.1%. The rates of MACCE and all-cause mortality were 9.7% and 5.2%, respectively, in the no organ damage group; 21.3% and 21.3% in CI-AKI group; 18.5% and 14.6% in HLI group; and 57.7% and 50.0% in combined CI-AKI and HLI group. Survival probability plots of composite MACCE and all-cause mortality revealed that the combined CI-AKI and HLI group was associated with the worst prognosis (p<0.0001 for both). Conclusion Combined CI-AKI after index procedure and HLI on admission is associated with poor clinical outcomes in patients with STEMI who underwent primary PCI. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.subject | PRIMARY ANGIOPLASTY | - |
dc.subject | HEART-FAILURE | - |
dc.subject | CARE UNIT | - |
dc.subject | HEPATITIS | - |
dc.subject | OUTCOMES | - |
dc.subject | MORTALITY | - |
dc.subject | SOCIETY | - |
dc.subject | TRENDS | - |
dc.title | Prognostic Impact of Combined Contrast-Induced Acute Kidney Injury and Hypoxic Liver Injury in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Results from INTERSTELLAR Registry | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000379579500127 | - |
dc.identifier.doi | 10.1371/journal.pone.0159416 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.11, no.7 | - |
dc.identifier.scopusid | 2-s2.0-84978380539 | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 11 | - |
dc.citation.number | 7 | - |
dc.contributor.affiliatedAuthor | Moon, Jeonggeun | - |
dc.contributor.affiliatedAuthor | Oh, Pyung Chun | - |
dc.contributor.affiliatedAuthor | Kang, WoongChol | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | PRIMARY ANGIOPLASTY | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordPlus | CARE UNIT | - |
dc.subject.keywordPlus | HEPATITIS | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | SOCIETY | - |
dc.subject.keywordPlus | TRENDS | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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