Preservative Effect of Chitosan with 1,3-Butylene Glycol as Natural Preservativein Cosmetic Formulation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정인근 | - |
dc.contributor.author | 이근무 | - |
dc.contributor.author | 황유진 | - |
dc.date.accessioned | 2021-06-24T01:40:17Z | - |
dc.date.available | 2021-06-24T01:40:17Z | - |
dc.date.created | 2021-06-24 | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 1229-4160 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81360 | - |
dc.description.abstract | This study was to evaluate the preservative effect of chitosan with 1,3-butylene glycol as natural preservative in cosmetic formulation. Antibacterial activity was measured by disc diffusion assay and broth microdilution assay were assessed on human skin microorganisms, Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and Escherichia coli. Antioxidant activity was measured by DPPH radical scavenging assay. Furthermore, an optimum formulation of chitosan with 1,3-butylene glycol was confirmed the preservative effect and cytotoxicity through challenge test and cell cytotoxicity assay. Chitosan showed remarkable antibacterial and antioxidant activities. A combination of chitosan with 1,3-butylene glycol exhibited higher activity compared to chitosan alone. Through results, the optimum formulation was determined to 156 μg/mL chitosan with 10% 1,3-butylene glycol (CTSN-BG). CTSN-BG showed a potent preservative effect and non-cytotoxicity on HaCaT and HEK 293 cells. In conclusion, the results demonstrated that CTSN-BG may be useful in a wide range of substitutes for chemical preservatives in cosmetic industry. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 한국키틴키토산학회 | - |
dc.relation.isPartOf | Journal of Chitin and Chitosan | - |
dc.title | Preservative Effect of Chitosan with 1,3-Butylene Glycol as Natural Preservativein Cosmetic Formulation | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.doi | 10.17642/jcc.26.2.4 | - |
dc.identifier.bibliographicCitation | Journal of Chitin and Chitosan, v.26, no.2, pp.69 - 75 | - |
dc.identifier.kciid | ART002725111 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 75 | - |
dc.citation.startPage | 69 | - |
dc.citation.title | Journal of Chitin and Chitosan | - |
dc.citation.volume | 26 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | 정인근 | - |
dc.contributor.affiliatedAuthor | 이근무 | - |
dc.contributor.affiliatedAuthor | 황유진 | - |
dc.subject.keywordAuthor | Chitosan | - |
dc.subject.keywordAuthor | 1 | - |
dc.subject.keywordAuthor | 3-Butylene glycol | - |
dc.subject.keywordAuthor | Preservative effect | - |
dc.subject.keywordAuthor | Natural preservative | - |
dc.subject.keywordAuthor | Cosmetic formulation | - |
dc.description.journalRegisteredClass | kci | - |
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