Low serum adiponectin level is associated with better physical health-related quality of life in chronic kidney disease
DC Field | Value | Language |
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dc.contributor.author | Kim, Ji Hye | - |
dc.contributor.author | Han, Ji Min | - |
dc.contributor.author | Kim, Hyang | - |
dc.contributor.author | Lee, Kyu-Beck | - |
dc.contributor.author | Chung, Wookyung | - |
dc.contributor.author | Kim, Yong-Soo | - |
dc.contributor.author | Park, Sue K. | - |
dc.contributor.author | Chae, Dong Wan | - |
dc.contributor.author | Ahn, Curie | - |
dc.contributor.author | Oh, Kook-Hwan | - |
dc.contributor.author | Hyun, Young Youl | - |
dc.date.accessioned | 2021-06-29T00:40:12Z | - |
dc.date.available | 2021-06-29T00:40:12Z | - |
dc.date.created | 2021-06-07 | - |
dc.date.issued | 2021-05-25 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81386 | - |
dc.description.abstract | Hyperadiponectemia is paradoxically associated with renal disease progression and mortality in chronic kidney disease (CKD). Its association with health-related quality of life (HR-QOL) is unknown. This study aimed to verify the association between adiponectin and HR-QOL in Korean pre-dialysis CKD cohort. This cross-sectional study analyzed 1551 pre-dialysis CKD patients from KNOW-CKD (KoreaN Cohort Study for Outcome in Patients With Chronic Kidney Disease). Participants were categorized into three tertiles (T1–T3) according to adiponectin levels. HR-QOL was assessed using SF-36. High physical component summary (PCS) and mental component summary (MCS) were defined as highest quartile of each score. Multivariate logistic regression was used to analyze odds ratio (OR) and 95% confidence interval (CI) for high PCS and MCS. Prevalence of high PCS were 33.3%, 27.5%, and 17.0% and that of high MCS were 31.7%, 24.8%, and 21.3% for T1, T2, and T3 (both p for trend < 0.001). The adjusted OR [95% CI] of T1 and T2 in reference to T3 were 1.56 [1.09–2.23] and 1.19 [0.85–1.68] for high PCS and 1.19 [0.85–1.68] and 0.94 [0.68–1.29] for high MCS. Serum adiponectin level was inversely associated with physical HR-QOL in Korean pre-dialysis CKD patients. This relationship was independent of various cardiovascular risk factors. © 2021, The Author(s). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Nature Research | - |
dc.relation.isPartOf | Scientific Reports | - |
dc.title | Low serum adiponectin level is associated with better physical health-related quality of life in chronic kidney disease | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000659136700016 | - |
dc.identifier.doi | 10.1038/s41598-021-90339-8 | - |
dc.identifier.bibliographicCitation | Scientific Reports, v.11, no.1 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85106919538 | - |
dc.citation.title | Scientific Reports | - |
dc.citation.volume | 11 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Chung, Wookyung | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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