Preliminary Comparison of Subcortical Structures in Elderly Subclinical Depression: Structural Analysis with 3T MRI
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임상진 | - |
dc.contributor.author | 이정환 | - |
dc.contributor.author | Siekyeong Kim | - |
dc.date.accessioned | 2021-07-02T10:40:16Z | - |
dc.date.available | 2021-07-02T10:40:16Z | - |
dc.date.created | 2021-05-14 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 1226-2560 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81445 | - |
dc.description.abstract | Depression in the elderly population has shown increased likelihood of neurological disorders due to structural changes in the subcortical area. However, further investigation into depression related subcortical changes is needed due to mismatches in structural analysis results between stud ies as well as scarcities in research regarding subcortical connectivity patterns of subclinical depression populations. This study aims to investigate structural differences in subcortical regions of aged participants with subclinical depression using 3Tesla MRI. In structural analysis, volumes of each subcortical region were measured to observe the volumetric difference and asymmetry between groups, but no significant difference was found. In addition, fractional anisotropy (FA) and apparent diffusion coefficient (ADC) did not show any significant differences between groups. Structural analysis using probabilistic tractography indicated that the connection strength between left nucleus accumbens-right hippocampus, and right thalamus-right caudate was higher in the control group than the subclinical depression group. The differences in subcortical connection strength of subclinical depression groups, have shown to correlate with emotional and cognitive disorders, such as anxiety and memory impair ment. We believe that the analysis of structural differences and cross-regional network measures in subcortical structures can help identify neuro physiological changes occurring in subclinical depression. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC BRAIN & NEURAL SCIENCE | - |
dc.relation.isPartOf | EXPERIMENTAL NEUROBIOLOGY | - |
dc.title | Preliminary Comparison of Subcortical Structures in Elderly Subclinical Depression: Structural Analysis with 3T MRI | - |
dc.title.alternative | Preliminary Comparison of Subcortical Structures in Elderly Subclinical Depression: Structural Analysis with 3T MRI | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000654000200007 | - |
dc.identifier.doi | 10.5607/en20056 | - |
dc.identifier.bibliographicCitation | EXPERIMENTAL NEUROBIOLOGY, v.30, no.2, pp.183 - 202 | - |
dc.identifier.kciid | ART002716172 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85106763444 | - |
dc.citation.endPage | 202 | - |
dc.citation.startPage | 183 | - |
dc.citation.title | EXPERIMENTAL NEUROBIOLOGY | - |
dc.citation.volume | 30 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | 임상진 | - |
dc.subject.keywordAuthor | Subclinical depression | - |
dc.subject.keywordAuthor | Brain | - |
dc.subject.keywordAuthor | Basal ganglia | - |
dc.subject.keywordAuthor | Volumetric | - |
dc.subject.keywordAuthor | Diffusion tensor imaging | - |
dc.subject.keywordAuthor | Tractography | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.