Investigation of the influence of TiO2 distribution on HA/TiO2 composite wetting ability using the dispersant SDBS, high-temperature annealing, and ultrasonication
DC Field | Value | Language |
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dc.contributor.author | Van Quy Hoang | - |
dc.contributor.author | Trung Hieu Vu | - |
dc.contributor.author | Hai Truyen Dang | - |
dc.contributor.author | Kim, Moon Il | - |
dc.contributor.author | Bark, Chung Wung | - |
dc.date.accessioned | 2021-07-04T03:41:12Z | - |
dc.date.available | 2021-07-04T03:41:12Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2021-07-01 | - |
dc.identifier.issn | 1748-6041 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81484 | - |
dc.description.abstract | The use of composites such as hydroxyapatite (HA)/TiO2 in bioapplications has attracted increasing attention in recent years. Herein, for the enhancement wetting ability and biocompatibility, the HA/TiO2 composite was subjected to different treatments to improve nanoparticle (NP) distribution and surface energy with an aim of mitigating nanotoxicity concerns. The treatments included ultrasonication, high-temperature annealing, and addition of a dispersant and surfactant, sodium dodecylbenzenesulfonate (SDBS). Contact angle measurement tests revealed the effect of SDBS addition on the distribution of TiO2 NPs on the HA surface: a decrease in the contact angle and, thus, an increase in the wetting ability of the HA/TiO2 composite were observed. The combination of annealing and SDBS addition treatments allowed for guest TiO2 particles to be uniformly distributed on the surface of the host HA particles, showing a rapid conversion from a hydrophobic to superhydrophilic property. In vitro investigation suggested that the cell viabilities of annealed HA/TiO2, SDBS-added HA/TiO2, and SDBS-added and annealed HA/TiO2 reached 89.7%, 94.7%, and 95.8%, respectively, while those of HA and untreated HA/TiO2 were 80.3% and 86.9%, respectively. The modified composites exhibited lower cytotoxicities than the unmodified systems (HA and HA/TiO2). Furthermore, the cell adhesion behavior of the composites was confirmed through actin-4 ',6-Diamidino-2-phenylindole (DAPI) staining, which showed negligible changes in the cytoskeleton architecture of the cells. This study confirmed that a modified HA/TiO2 composite has potential for bioapplications. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | IOP PUBLISHING LTD | - |
dc.relation.isPartOf | BIOMEDICAL MATERIALS | - |
dc.title | Investigation of the influence of TiO2 distribution on HA/TiO2 composite wetting ability using the dispersant SDBS, high-temperature annealing, and ultrasonication | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000658870500001 | - |
dc.identifier.doi | 10.1088/1748-605X/ac0591 | - |
dc.identifier.bibliographicCitation | BIOMEDICAL MATERIALS, v.16, no.4 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85108020681 | - |
dc.citation.title | BIOMEDICAL MATERIALS | - |
dc.citation.volume | 16 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Van Quy Hoang | - |
dc.contributor.affiliatedAuthor | Trung Hieu Vu | - |
dc.contributor.affiliatedAuthor | Hai Truyen Dang | - |
dc.contributor.affiliatedAuthor | Kim, Moon Il | - |
dc.contributor.affiliatedAuthor | Bark, Chung Wung | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | hydroxyapatite (HA) | - |
dc.subject.keywordAuthor | TiO2 | - |
dc.subject.keywordAuthor | surfactant SDBS | - |
dc.subject.keywordAuthor | dispersion | - |
dc.subject.keywordPlus | TITANIUM | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | PARTICLES | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | DEPOSITION | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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