Ultrasensitive biosensors based on waveguide-coupled long-range surface plasmon resonance (WC-LRSPR) for enhanced fluorescence spectroscopy
DC Field | Value | Language |
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dc.contributor.author | Thi, Tran N.H. | - |
dc.contributor.author | Phung, V.-D. | - |
dc.contributor.author | Thi, Ta H.K. | - |
dc.contributor.author | Lam, V.D. | - |
dc.contributor.author | Manh, D.H. | - |
dc.contributor.author | Pham, N.K. | - |
dc.contributor.author | Kim, Jae Young | - |
dc.contributor.author | Lee, Nae Yoon | - |
dc.contributor.author | Phan, B.T. | - |
dc.date.accessioned | 2021-07-14T23:40:36Z | - |
dc.date.available | 2021-07-14T23:40:36Z | - |
dc.date.created | 2021-07-07 | - |
dc.date.issued | 2021-07-03 | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81676 | - |
dc.description.abstract | We investigated the coupling phenomenon between plasmonic resonance and waveguide modes through theoretical and experimental parametric analyses on the bimetallic waveguide-coupled long-range surface plasmon resonance (Bi-WCLRSPR) structure. The calculation results indicated that the multi-plasmonic coupling gives rise to the enhanced depth-to-width ratio of the reflection dip compared to that of LRSPR excited using a single set of Ag and Teflon. The optimized thickness of Ag(40 nm)/Teflon(700 nm)/Ag(5 nm)/Au(5 nm) was obtained and generated the highest plasmon intensity enhancement, which was 2.38 folds in comparison to the conventional bimetallic surface plasmon resonance (SPR) configuration (Ag/Au). 17β-Estradiol was used in the fluorescence enhancement experiment by the reflection geometry-based system, wherein the excitation light source was on the side of a WC-LRSPR chip opposite to that of the light detection unit. The phenomenon of surface plasmon-couple emission (SPCE) depends on the number of 17β-estradiol molecule promoters from female sex steroid hormones, which demonstrated a limit of detection (LOD) of 2 pg mL−1and 1.47-fold fluorescence improvement as compared to the non-coated material on the surface of pristine glass. This enhanced WC-LRSPR can readily find application in fluorescence escalation needed in cases where a weak fluorescence signal is predicted, such as the small volume of liquid containing fluorescent dyes in biological diagnosis. © The Royal Society of Chemistry 2021. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Royal Society of Chemistry | - |
dc.relation.isPartOf | RSC Advances | - |
dc.title | Ultrasensitive biosensors based on waveguide-coupled long-range surface plasmon resonance (WC-LRSPR) for enhanced fluorescence spectroscopy | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000667711300058 | - |
dc.identifier.doi | 10.1039/d1ra02130c | - |
dc.identifier.bibliographicCitation | RSC Advances, v.11, no.36, pp.22450 - 22460 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85108891635 | - |
dc.citation.endPage | 22460 | - |
dc.citation.startPage | 22450 | - |
dc.citation.title | RSC Advances | - |
dc.citation.volume | 11 | - |
dc.citation.number | 36 | - |
dc.contributor.affiliatedAuthor | Kim, Jae Young | - |
dc.contributor.affiliatedAuthor | Lee, Nae Yoon | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | Coated materials | - |
dc.subject.keywordPlus | Fiber optic sensors | - |
dc.subject.keywordPlus | Fluorescence | - |
dc.subject.keywordPlus | Fluorescence spectroscopy | - |
dc.subject.keywordPlus | Light sources | - |
dc.subject.keywordPlus | Plasmons | - |
dc.subject.keywordPlus | Resonance | - |
dc.subject.keywordPlus | Steroid hormones | - |
dc.subject.keywordPlus | Waveguides | - |
dc.subject.keywordPlus | Excitation light sources | - |
dc.subject.keywordPlus | Fluorescence enhancement | - |
dc.subject.keywordPlus | Fluorescence signals | - |
dc.subject.keywordPlus | Intensity enhancement | - |
dc.subject.keywordPlus | Long-range surface plasmons | - |
dc.subject.keywordPlus | Parametric -analysis | - |
dc.subject.keywordPlus | Plasmonic resonances | - |
dc.subject.keywordPlus | Sex steroid hormones | - |
dc.subject.keywordPlus | Surface plasmon resonance | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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