Diagnostic Performance of 2018 KLCA-NCC Practice Guideline for Hepatocellular Carcinoma on Gadoxetic Acid-Enhanced MRI in Patients with Chronic Hepatitis B or Cirrhosis: Comparison with LI-RADS Version 2018
DC Field | Value | Language |
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dc.contributor.author | Lee Sang Min | - |
dc.contributor.author | Lee Jeong Min | - |
dc.contributor.author | Ahn Su Joa | - |
dc.contributor.author | Kang Hyo-Jin | - |
dc.contributor.author | Yang Hyun Kyung | - |
dc.contributor.author | Yoon Jeong Hee | - |
dc.date.accessioned | 2021-08-09T00:40:30Z | - |
dc.date.available | 2021-08-09T00:40:30Z | - |
dc.date.created | 2021-06-27 | - |
dc.date.issued | 2021-07 | - |
dc.identifier.issn | 1229-6929 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81833 | - |
dc.description.abstract | Objective: To evaluate the performance of the 2018 Korean Liver Cancer Association-National Cancer Center (KLCA-NCC) Practice Guidelines (hereafter, PG) for the diagnosis of hepatocellular carcinoma (HCC) using gadoxetic acid-enhanced MRI, compared to the Liver Imaging-Reporting and Data System (LI-RADS) version 2018 (hereafter, v2018). Materials and Methods: From January 2013 to October 2015, treatment-naïve hepatic lesions (≥ 1 cm) on gadoxetic acidenhanced MRI in consecutive patients with chronic hepatitis B or cirrhosis were retrospectively evaluated. For each lesion, three radiologists independently analyzed the imaging features and classified the lesions into categories according to the 2018 KLCA-NCC PG and LI-RADS v2018. The imaging features and categories were determined by consensus. Generalized estimating equation (GEE) models were used to compare the per-lesion diagnostic performance of the 2018 KLCA-NCC PG and LI-RADS v2018 using the consensus data. Results: In total, 422 lesions (234 HCCs, 45 non-HCC malignancies, and 143 benign lesions) from 387 patients (79% male; mean age, 59 years) were included. In all lesions, the definite HCC (2018 KLCA-NCC PG) had a higher sensitivity and lower specificity than LR-5 (LI-RADS v2018) (87.2% [204/234] vs. 80.8% [189/234], p < 0.001; 86.2% [162/188] vs. 91.0% [171/188], p = 0.002). However, in lesions of size ≥ 2 cm, the definite HCC had a higher sensitivity than the LR-5 (86.8% [164/189] vs. 82.0 (155/189), p = 0.002) without a reduction in the specificity (80.0% [48/60] vs. 83.3% [50/60], p = 0.15). In all lesions, the sensitivity and specificity of the definite/probable HCC (2018 KLCA-NCC PG) and LR-5/4 did not differ significantly (89.7% [210/234] vs. 91.5% [214/234], p = 0.204; 83.5% [157/188] vs. 79.3% [149/188], p = 0.071). Conclusion: For the diagnosis of HCC of size ≥ 2 cm, the definite HCC (2018 KLCA-NCC PG) had a higher sensitivity than LR-5, without a reduction in specificity. The definite/probable HCC (2018 KLCA-NCC PG) had a similar sensitivity and specificity to that those of the LR-5/4. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한영상의학회 | - |
dc.relation.isPartOf | Korean Journal of Radiology | - |
dc.title | Diagnostic Performance of 2018 KLCA-NCC Practice Guideline for Hepatocellular Carcinoma on Gadoxetic Acid-Enhanced MRI in Patients with Chronic Hepatitis B or Cirrhosis: Comparison with LI-RADS Version 2018 | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000669545800006 | - |
dc.identifier.doi | 10.3348/kjr.2020.0846 | - |
dc.identifier.bibliographicCitation | Korean Journal of Radiology, v.22, no.7, pp.1066 - 1076 | - |
dc.identifier.kciid | ART002725396 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85111784487 | - |
dc.citation.endPage | 1076 | - |
dc.citation.startPage | 1066 | - |
dc.citation.title | Korean Journal of Radiology | - |
dc.citation.volume | 22 | - |
dc.citation.number | 7 | - |
dc.contributor.affiliatedAuthor | Ahn Su Joa | - |
dc.subject.keywordAuthor | Diagnosis | - |
dc.subject.keywordAuthor | Liver neoplasm | - |
dc.subject.keywordAuthor | Hepatocellular carcinoma | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.subject.keywordAuthor | Gadoxetic acid | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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