Nanosilver-embedded silicon nanowires as a SERS-active substrate for the ultrasensitive detection of monoamine neurotransmitters
DC Field | Value | Language |
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dc.contributor.author | Vo, Van-The | - |
dc.contributor.author | Phung, Viet-Duc | - |
dc.contributor.author | Lee, Sang-Wha | - |
dc.date.accessioned | 2021-08-12T05:40:23Z | - |
dc.date.available | 2021-08-12T05:40:23Z | - |
dc.date.created | 2021-06-21 | - |
dc.date.issued | 2021-08 | - |
dc.identifier.issn | 2468-0230 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81850 | - |
dc.description.abstract | The trace detection of neurotransmitters is very useful in the diagnosis of severe neuropsychiatric diseases such as Parkinson's, Schizophrenia, and Depression. Surface enhanced Raman scattering (SERS) is a prospective technique for the sensitive detection of analyte with molecular information. Herein, a porous silicon (pSi) template (so-called silicon nanowires) was prepared using a metal-assisted chemical etching process, and the pSi template was successfully embedded with plenty of nanosilvers. The nanosilver-embedded pSi (pSi@Ag) was employed as a SERS-active substrate to detect dopamine (DA) and serotonin (ST) neurotransmitters at ultralow concentrations. The optimized pSi@Ag substrate produced an excellent dynamic linear range over six orders of magnitude (from 10−6 to 10−12 M), as well as showing the picomolar detection limit of ~10−13 M. The substrate exhibited the comparable performance to the current state-of-the-art researches, probably because the SERS signals were generated from larger number of analyte molecules adsorbed on the internal silver nanostructures with porous layer. Furthermore, the pSi@Ag substrate distinguished the individual component in the mixture (DA and ST at 10−8 M) without any labelling, corroborating the reliable pSi@Ag substrate for the application to the actual biological fluid. © 2021 | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.relation.isPartOf | Surfaces and Interfaces | - |
dc.title | Nanosilver-embedded silicon nanowires as a SERS-active substrate for the ultrasensitive detection of monoamine neurotransmitters | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000681243600002 | - |
dc.identifier.doi | 10.1016/j.surfin.2021.101181 | - |
dc.identifier.bibliographicCitation | Surfaces and Interfaces, v.25 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85107896311 | - |
dc.citation.title | Surfaces and Interfaces | - |
dc.citation.volume | 25 | - |
dc.contributor.affiliatedAuthor | Vo, Van-The | - |
dc.contributor.affiliatedAuthor | Lee, Sang-Wha | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Dopamine | - |
dc.subject.keywordAuthor | Nanosilver-embedded | - |
dc.subject.keywordAuthor | Serotonin | - |
dc.subject.keywordAuthor | SERS | - |
dc.subject.keywordAuthor | Silicon nanowires | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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