Multiscale pore contained carbon nanofiber-based field-effect transistor biosensors for nesfatin-1 detection
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Sung Gun | - |
dc.contributor.author | Lee, Jun Seop | - |
dc.date.accessioned | 2021-08-12T12:40:03Z | - |
dc.date.available | 2021-08-12T12:40:03Z | - |
dc.date.created | 2021-07-28 | - |
dc.date.issued | 2021-08-14 | - |
dc.identifier.issn | 2050-7518 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81856 | - |
dc.description.abstract | Nesfatin-1 (NES1) is a potential biomarker found in serum and saliva that indicates hyperpolarization and depolarization in the hypothalamic ventricle nucleus as well as an increase in epileptic conditions. However, real-time investigations have not been carried out to detect changes in the concentration of NES1. In this study, we develop a multiscale pore contained carbon nanofiber-based field-effect transistor (FET) biosensor to detect NES1. The activated multiscale pore contained carbon nanofiber (a-MPCNF) is generated using a single-nozzle co-electrospinning method and a subsequent steam-activation process to obtain a signal transducer and template for immobilization of bioreceptors. The prepared biosensor exhibits a high sensitivity to NES1. It can detect levels as low as 0.1 fM of NES1, even in the presence of other interfering biomolecules. Furthermore, the a-MPCNF-based FET sensor has significant potential for practical applications in non-invasive real-time diagnosis, as indicated by its sensing performance in artificial saliva. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.relation.isPartOf | JOURNAL OF MATERIALS CHEMISTRY B | - |
dc.title | Multiscale pore contained carbon nanofiber-based field-effect transistor biosensors for nesfatin-1 detection | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000674764000001 | - |
dc.identifier.doi | 10.1039/d1tb00582k | - |
dc.identifier.bibliographicCitation | JOURNAL OF MATERIALS CHEMISTRY B, v.9, no.30, pp.6076 - 6083 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85112625401 | - |
dc.citation.endPage | 6083 | - |
dc.citation.startPage | 6076 | - |
dc.citation.title | JOURNAL OF MATERIALS CHEMISTRY B | - |
dc.citation.volume | 9 | - |
dc.citation.number | 30 | - |
dc.contributor.affiliatedAuthor | Lee, Jun Seop | - |
dc.type.docType | Article; Early Access | - |
dc.subject.keywordPlus | SERUM PROLACTIN | - |
dc.subject.keywordPlus | TIME | - |
dc.subject.keywordPlus | BIOMARKER | - |
dc.subject.keywordPlus | SEIZURES | - |
dc.subject.keywordPlus | MARKER | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.