Smoking Cessation and Coronary Artery Calcification in CKD
DC Field | Value | Language |
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dc.contributor.author | Lee, Mi Jung | - |
dc.contributor.author | Park, Jung Tak | - |
dc.contributor.author | Chang, Tae Ik | - |
dc.contributor.author | Joo, Young Su | - |
dc.contributor.author | Yoo, Tae-Hyun | - |
dc.contributor.author | Park, Sue Kyung | - |
dc.contributor.author | Chung, Wookyung | - |
dc.contributor.author | Kim, Yong-Soo | - |
dc.contributor.author | Kim, Soo Wan | - |
dc.contributor.author | Oh, Kook-Hwan | - |
dc.contributor.author | Kang, Shin-Wook | - |
dc.contributor.author | Choi, Kyu Hun | - |
dc.contributor.author | Ahn, Curie | - |
dc.contributor.author | Han, Seung Hyeok | - |
dc.date.accessioned | 2021-08-20T03:40:11Z | - |
dc.date.available | 2021-08-20T03:40:11Z | - |
dc.date.created | 2021-06-29 | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 1555-9041 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81902 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVES: Smoking is associated with vascular calcification and a higher risk of cardiovascular disease. In this study, we investigated the association of smoking dose and cessation with coronary artery calcification (CAC) in patients with CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: From a nationwide, prospective cohort of Korean patients with CKD, 1914 participants were included. Prevalent CAC was defined as an Agatston score >0, using computed tomography. CAC progression was defined as ≥30%/yr increase in Agatston score at the 4-year follow-up examination in patients with baseline CAC. RESULTS: Prevalent CAC was observed in 952 (50%) patients. Compared with never smokers, former smokers had a similar prevalence ratio for CAC, but current smokers had a 1.25-fold higher prevalence ratio (95% confidence interval [95% CI], 1.10 to 1.42). Among former smokers, a lower smoking load of <10 pack-years (prevalence ratio, 0.77; 95% CI, 0.65 to 0.90) and longer duration of smoking cessation (prevalence ratio for 10 to <20 years, 0.85; 95% CI, 0.73 to 0.98: prevalence ratio for ≥20 years, 0.83; 95% CI, 0.73 to 0.96) were associated with lower risk of prevalent CAC compared with current smoking. The prevalence ratios did not differ between never smoking and long-term cessation. However, short-term cessation with heavy smoking load was associated with a higher risk of prevalent CAC (prevalence ratio, 1.21; 95% CI, 1.03 to 1.40) compared with never smoking. CAC progression was observed in 111 (33%) patients with baseline CAC. Compared with never smokers, former smokers showed a similar risk of CAC progression, but current smokers had a higher risk (relative risk, 1.92; 95% CI, 1.30 to 2.86). CONCLUSIONS: In CKD, former smoking with a lower smoking load and long-term cessation were associated with a lower risk of prevalent CAC than current smoking. CAC progression was more pronounced in current smokers. Copyright © 2021 by the American Society of Nephrology. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER SOC NEPHROLOGY | - |
dc.relation.isPartOf | CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | - |
dc.title | Smoking Cessation and Coronary Artery Calcification in CKD | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000682991600009 | - |
dc.identifier.doi | 10.2215/CJN.15751020 | - |
dc.identifier.bibliographicCitation | CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, v.16, no.6, pp.870 - 879 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85108304026 | - |
dc.citation.endPage | 879 | - |
dc.citation.startPage | 870 | - |
dc.citation.title | CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | - |
dc.citation.volume | 16 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Chung, Wookyung | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | cardiovascular disease | - |
dc.subject.keywordAuthor | chronic kidney disease | - |
dc.subject.keywordAuthor | coronary artery disease | - |
dc.subject.keywordAuthor | coronary calcification | - |
dc.subject.keywordAuthor | smoking | - |
dc.subject.keywordAuthor | smoking cessation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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