Comparison of remifentanil EC50 for facilitating i-gel and laryngeal mask airway insertion with propofol anesthesia
DC Field | Value | Language |
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dc.contributor.author | Choi, Jong Bum | - |
dc.contributor.author | Kwak, Hyun Jeong | - |
dc.contributor.author | Lee, Kyung Cheon | - |
dc.contributor.author | Lee, Se Ryeon | - |
dc.contributor.author | Lee, Sook Young | - |
dc.contributor.author | Kim, Jong Yeop | - |
dc.date.available | 2020-02-28T01:44:52Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2016-06 | - |
dc.identifier.issn | 0913-8668 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8239 | - |
dc.description.abstract | Each supraglottic airway requires different anesthetic depth because it has a specific structure and different compressive force in the oropharyngeal cavity. We designed the study to compare the effect-site concentration (Ce) of remifentanil in 50 % of patients (EC50) for successful insertion of the i-gel second-generation supraglottic airway device with that for laryngeal mask airway (LMA) insertion during target-controlled infusion (TCI) of propofol. Forty-one female patients were randomized to the i-gel group (n = 20) or the LMA group (n = 21). Anesthesia was induced with propofol Ce of 5 mu g/ml and the predetermined remifentanil Ce, and the i-gel or LMA was inserted 5 min later. The remifentanil Ce was estimated by modified Dixon's up-and-down method (initial concentration: 3.0 ng/ml, step size: 0.5 ng/ml). The patient's response to device insertion was classified as either "success (no movement)" or "failure (movement)". Using the Dixon's up-and-down method, EC50 of remifentanil Ce for the i-gel (1.58 +/- 0.41 ng/ml) was significantly lower than that for LMA (2.25 +/- 0.55 ng/ml) (p = 0.038). Using isotonic regression, EC50 (83 % CI) of remifentanil in the i-gel group [1.50 (1.37-1.80) ng/ml] was statistically lower than that in the LMA group [2.00 (1.82-2.34) ng/ml]. EC95 (95 % CI) of remifentanil in the i-gel group [2.38 (1.48-2.50) ng/ml] was statistically lower than that in the LMA group [3.35 (2.58-3.48) ng/ml]. We found that EC50 of remifentanil Ce for i-gel insertion (1.58 ng/ml) was significantly lower than that for LMA insertion (2.25 ng/ml) in female patients during propofol TCI without neuromuscular blockade. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER JAPAN KK | - |
dc.relation.isPartOf | JOURNAL OF ANESTHESIA | - |
dc.subject | TARGET-CONTROLLED INFUSION | - |
dc.subject | SUPRAGLOTTIC AIRWAY | - |
dc.subject | CONFIDENCE-INTERVALS | - |
dc.subject | REQUIREMENTS | - |
dc.subject | INDUCTION | - |
dc.subject | DESIGN | - |
dc.subject | TERMS | - |
dc.subject | TUBE | - |
dc.subject | CUFF | - |
dc.title | Comparison of remifentanil EC50 for facilitating i-gel and laryngeal mask airway insertion with propofol anesthesia | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000376675600003 | - |
dc.identifier.doi | 10.1007/s00540-015-2133-6 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ANESTHESIA, v.30, no.3, pp.377 - 383 | - |
dc.identifier.scopusid | 2-s2.0-84954329065 | - |
dc.citation.endPage | 383 | - |
dc.citation.startPage | 377 | - |
dc.citation.title | JOURNAL OF ANESTHESIA | - |
dc.citation.volume | 30 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Kwak, Hyun Jeong | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Cheon | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | i-gel | - |
dc.subject.keywordAuthor | Laryngeal mask airway | - |
dc.subject.keywordAuthor | Remifentanil | - |
dc.subject.keywordPlus | TARGET-CONTROLLED INFUSION | - |
dc.subject.keywordPlus | SUPRAGLOTTIC AIRWAY | - |
dc.subject.keywordPlus | CONFIDENCE-INTERVALS | - |
dc.subject.keywordPlus | REQUIREMENTS | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | DESIGN | - |
dc.subject.keywordPlus | TERMS | - |
dc.subject.keywordPlus | TUBE | - |
dc.subject.keywordPlus | CUFF | - |
dc.relation.journalResearchArea | Anesthesiology | - |
dc.relation.journalWebOfScienceCategory | Anesthesiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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