Seven-Year Clinical Outcomes of Successful Versus Failed Revascularization Using Drug-Eluting Stents for the Treatment of Coronary Chronic Total Occlusion
- Authors
- Park, Jong-Pil; Han, Seungbong; Sung, Ki-Chul; Lee, Jong-Young; Choi, Hyo-In
- Issue Date
- Jun-2016
- Publisher
- H M P COMMUNICATIONS
- Keywords
- chronic total occlusion; drug-eluting stent; high-risk PCI
- Citation
- JOURNAL OF INVASIVE CARDIOLOGY, v.28, no.6, pp.229 - 236
- Journal Title
- JOURNAL OF INVASIVE CARDIOLOGY
- Volume
- 28
- Number
- 6
- Start Page
- 229
- End Page
- 236
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8272
- ISSN
- 1042-3931
- Abstract
- Objectives. The aim of our study is to investigate the long-term, 7-year clinical outcomes of patients who received successful or failed revascularization using a drug-eluting stent (DES) for the treatment of chronic total occlusion (CTO). Background. The benefits of successful CTO revascularization remain unclear. Methods. In this prospective cohort study, a total of 377 consecutive CTO patients were divided according to successful (n = 253) or failed (n = 124) DES revascularization. We compared a composite index that consisted of death, myocardial infarction (MI), stroke, and target-vessel revascularization (TVR) at 7 years using propensity matching and inverse probability of treatment weighted (IPTW) analyses. Results. After a median follow-up period of 2561 days (interquartile range, 1533-2996 days), the successful-revascularization group demonstrated numerically lower incidence of the composite endpoint than the failed-revascularization group (26.5% vs 34.3%, respectively; log-rank P=. 27). After IPTW adjustment, the risk of clinical outcomes (hazard ratio, 1.00; 95% confidence interval, 0.58-1.74; P=. 99) was not statistically different between the groups. Propensity-score matching analysis (91 matched pairs) revealed similar outcomes (hazard ratio, 1.09; 95% confidence interval, 0.62-1.90; P=. 77). Conclusions. Successful CTO revascularization does not demonstrate beneficial long-term clinical outcomes over 7 years compared with failed revascularization.
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