Kamut (Triticum turgidum spp.) 식빵 급여가 고지방식이 유도 비만 C57BL/6 마우스에 미치는 효과
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정현기 | - |
dc.contributor.author | 백지윤 | - |
dc.contributor.author | 최예정 | - |
dc.contributor.author | 강기성 | - |
dc.contributor.author | 김현영 | - |
dc.contributor.author | 김지현 | - |
dc.contributor.author | 최진상 | - |
dc.date.accessioned | 2021-12-30T06:40:12Z | - |
dc.date.available | 2021-12-30T06:40:12Z | - |
dc.date.created | 2021-12-30 | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 1976-9334 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83036 | - |
dc.description.abstract | Objectives: The purpose of this study was to investigate the effect of white pan bread added with Kamut (Triticum turgidum spp.) on high fat diet (HFD)-induced obese C57BL/6 mice. Methods: The white pan bread or white pan bread with Kamut (BK) were administered for 8 weeks in HFD-induced obese C57BL/6 mice. To evaluate the effect and its mechanisms of BK on obese mice, we measured body weight change, serum lipid profiles, histopathological analysis, and protein expression of CCAAT/enhancer binding protein-α (C/EBPα) in the liver. Results: Administration of BK significantly decreased body weight in HFD-induced obese mice. In addition, BK-administered group significantly reduced serum total cholesterol, glucose, and high-density lipoprotein cholesterol levels compared with the HFD-induced control group. The HFD-induced mice had damaged liver tissue and increased the size of adipose tissue, but BK-administered group attenuated liver damage and decreased the size of adipocyte. Furthermore, administration of BK significantly down-regulated C/EBPα in the liver compared with HFD-fed mice. In particular, BK-administered group has higher inhibited body weight, serum lipid profiles, and C/EBPα expressions than white pan bread-administered group. Conclusions: This study demonstrated that administration of BK attenuated HFD-induced obesity by regulation of C/EBPα than consumption of white pan bread. Therefore, BK could be developed as a bread for prevention of obesity. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 한방비만학회 | - |
dc.relation.isPartOf | 한방비만학회지 | - |
dc.title | Kamut (Triticum turgidum spp.) 식빵 급여가 고지방식이 유도 비만 C57BL/6 마우스에 미치는 효과 | - |
dc.title.alternative | Effects of White Pan Bread Added with Kamut (Triticum turgidum spp.) on High Fat Diet-Induced Obese C57BL/6 Mice | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.doi | 10.15429/jkomor.2021.21.2.49 | - |
dc.identifier.bibliographicCitation | 한방비만학회지, v.21, no.2, pp.49 - 58 | - |
dc.identifier.kciid | ART002789305 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 58 | - |
dc.citation.startPage | 49 | - |
dc.citation.title | 한방비만학회지 | - |
dc.citation.volume | 21 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | 최예정 | - |
dc.contributor.affiliatedAuthor | 강기성 | - |
dc.subject.keywordAuthor | High-fat diet | - |
dc.subject.keywordAuthor | Obesity | - |
dc.subject.keywordAuthor | Triticum | - |
dc.subject.keywordAuthor | Kamut | - |
dc.subject.keywordAuthor | White pan bread | - |
dc.description.journalRegisteredClass | kci | - |
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