Renal denervation for treatment of uncontrolled hypertension in an Asian population: results from the Global SYMPLICITY Registry in South Korea (GSR Korea)
DC Field | Value | Language |
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dc.contributor.author | Kim, B-K | - |
dc.contributor.author | Boehm, M. | - |
dc.contributor.author | Mahfoud, F. | - |
dc.contributor.author | Mancia, G. | - |
dc.contributor.author | Park, S. | - |
dc.contributor.author | Hong, M-K | - |
dc.contributor.author | Kim, H-S | - |
dc.contributor.author | Park, S-J | - |
dc.contributor.author | Park, C. G. | - |
dc.contributor.author | Seung, K. B. | - |
dc.contributor.author | Gwon, H-C | - |
dc.contributor.author | Choi, D-J | - |
dc.contributor.author | Ahn, T. H. | - |
dc.contributor.author | Kim, C. J. | - |
dc.contributor.author | Kwon, H. M. | - |
dc.contributor.author | Esler, M. | - |
dc.contributor.author | Jang, Y. S. | - |
dc.date.available | 2020-02-28T01:46:17Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2016-05 | - |
dc.identifier.issn | 0950-9240 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8319 | - |
dc.description.abstract | Reports detailing the response of hypertensive patients to renal denervation (RDN) in Asian patients are limited. We evaluated 6- and 12-month outcomes after RDN in an Asian population and compared outcomes to a primarily Caucasian population. The Global SYMPLICITY Registry (GSR) is a prospective, all-comer, worldwide registry that evaluates the safety and effectiveness of RDN and includes the Korean registry substudy (GSR Korea) and a Caucasian subset (GSR Caucasian). Given differences in baseline characteristics among GSR Korea (n = 93) as compared with GSR Caucasian (n = 169) patients, including lower baseline office systolic blood pressure (SBP), lower body mass index and differences in medications, propensity score adjustment was performed when comparing the change in SBP between subsets. The 6- and 12-month change in SBP in GSR Korea was -19.4 +/- 17.2 and -27.2 +/- 18.1 mm Hg, respectively (P < 0.001 for both vs baseline). GSR Caucasian had a SBP change similar to GSR Korea at 6 months (-20.9 +/- 21.4 mm Hg, unadjusted P = 0.547, adjusted P = 0.998), whereas at 12 months the change was significantly less pronounced (-20.1 +/- 23.9 mm Hg, unadjusted P = 0.004, adjusted P = 0.002). There were no protocol-defined procedure-related adverse events and no chronic adverse events associated with the device in an Asian population. RDN provided a significant reduction in 6- and 12-month office SBP among Asian patients, with a favorable safety profile. The 12-month SBP reduction was larger than that observed in Caucasian patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.relation.isPartOf | JOURNAL OF HUMAN HYPERTENSION | - |
dc.subject | FILTRATION-RATE ESTIMATION | - |
dc.subject | BODY-MASS INDEX | - |
dc.subject | SYMPATHETIC DENERVATION | - |
dc.subject | BLOOD-PRESSURE | - |
dc.subject | DISEASE | - |
dc.subject | EQUATION | - |
dc.subject | DIET | - |
dc.title | Renal denervation for treatment of uncontrolled hypertension in an Asian population: results from the Global SYMPLICITY Registry in South Korea (GSR Korea) | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000374123800006 | - |
dc.identifier.doi | 10.1038/jhh.2015.77 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HUMAN HYPERTENSION, v.30, no.5, pp.315 - 321 | - |
dc.identifier.scopusid | 2-s2.0-84936966641 | - |
dc.citation.endPage | 321 | - |
dc.citation.startPage | 315 | - |
dc.citation.title | JOURNAL OF HUMAN HYPERTENSION | - |
dc.citation.volume | 30 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Ahn, T. H. | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | FILTRATION-RATE ESTIMATION | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | SYMPATHETIC DENERVATION | - |
dc.subject.keywordPlus | BLOOD-PRESSURE | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | EQUATION | - |
dc.subject.keywordPlus | DIET | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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