Depsidomycins B and C: New Cyclic Peptides from a Ginseng Farm Soil-Derived Actinomycete
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwon, Yun | - |
dc.contributor.author | Byun, Woong Sub | - |
dc.contributor.author | Kim, Byung-Yong | - |
dc.contributor.author | Song, Myoung Chong | - |
dc.contributor.author | Bae, Munhyung | - |
dc.contributor.author | Yoon, Yeo Joon | - |
dc.contributor.author | Shin, Jongheon | - |
dc.contributor.author | Lee, Sang Kook | - |
dc.contributor.author | Oh, Dong-Chan | - |
dc.date.accessioned | 2022-01-19T06:41:24Z | - |
dc.date.available | 2022-01-19T06:41:24Z | - |
dc.date.created | 2022-01-19 | - |
dc.date.issued | 2018-06 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83306 | - |
dc.description.abstract | LC/MS-based chemical profiling of a ginseng farm soil-derived actinomycete strain, Streptomyces sp. BYK1371, enabled the discovery of two new cyclic heptapeptides, depsidomycins B and C (1 and 2), each containing two piperazic acid units and a formyl group at their N-terminus. The structures of 1 and 2 were elucidated by a combination of spectroscopic and chemical analyses. These new compounds were determined to possess D-leucine, D-threonine, D-valine, and S-piperazic acid based on the advanced Marfey's method and a GITC (2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate) derivatization of their hydrolysates, followed by LC/MS analysis. Depsidomycins B and C displayed significant antimetastatic activities against metastatic breast cancer cells (MDA-MB-231). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | MOLECULES | - |
dc.title | Depsidomycins B and C: New Cyclic Peptides from a Ginseng Farm Soil-Derived Actinomycete | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000435875400028 | - |
dc.identifier.doi | 10.3390/molecules23061266 | - |
dc.identifier.bibliographicCitation | MOLECULES, v.23, no.6 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85047857096 | - |
dc.citation.title | MOLECULES | - |
dc.citation.volume | 23 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Bae, Munhyung | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | farm soil | - |
dc.subject.keywordAuthor | actinomycete | - |
dc.subject.keywordAuthor | Streptomyces sp. | - |
dc.subject.keywordAuthor | cyclic peptide | - |
dc.subject.keywordAuthor | antimetastatic | - |
dc.subject.keywordPlus | CONSTITUENT AMINO-ACIDS | - |
dc.subject.keywordPlus | ABSOLUTE-CONFIGURATION | - |
dc.subject.keywordPlus | MASS-SPECTROMETRY | - |
dc.subject.keywordPlus | MARFEYS METHOD | - |
dc.subject.keywordPlus | GUT BACTERIUM | - |
dc.subject.keywordPlus | BEETLE | - |
dc.subject.keywordPlus | LC/MS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.