A New Benzofuran Glycoside and Indole Alkaloids from a Sponge-Associated Rare Actinomycete, Amycolatopsis sp.
DC Field | Value | Language |
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dc.contributor.author | Kwon, Yun | - |
dc.contributor.author | Kim, Seong-Hwan | - |
dc.contributor.author | Shin, Yoonho | - |
dc.contributor.author | Bae, Munhyung | - |
dc.contributor.author | Kim, Byung-Yong | - |
dc.contributor.author | Lee, Sang Kook | - |
dc.contributor.author | Oh, Ki-Bong | - |
dc.contributor.author | Shin, Jongheon | - |
dc.contributor.author | Oh, Dong-Chan | - |
dc.date.accessioned | 2022-01-19T06:41:52Z | - |
dc.date.available | 2022-01-19T06:41:52Z | - |
dc.date.created | 2022-01-19 | - |
dc.date.issued | 2014-04 | - |
dc.identifier.issn | 1660-3397 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83314 | - |
dc.description.abstract | Three new secondary metabolites, amycofuran (1), amycocyclopiazonic acid (2), and amycolactam (3), were isolated from the sponge-associated rare actinomycete Amycolatopsis sp. Based on combined spectroscopic analyses, the structures of 1-3 were determined to be a new benzofuran glycoside and new indole alkaloids related to cyclopiazonic acids, a class that has previously only been reported in fungi. The absolute configurations of 1 and 3 were deduced by ECD calculations, whereas that of 2 was determined using the modified Mosher method. Amycolactam (3) displayed significant cytotoxicity against the gastric cancer cell line SNU638 and the colon cancer cell line HCT116. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | MARINE DRUGS | - |
dc.title | A New Benzofuran Glycoside and Indole Alkaloids from a Sponge-Associated Rare Actinomycete, Amycolatopsis sp. | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000335759500035 | - |
dc.identifier.doi | 10.3390/md12042326 | - |
dc.identifier.bibliographicCitation | MARINE DRUGS, v.12, no.4, pp.2326 - 2340 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84900394773 | - |
dc.citation.endPage | 2340 | - |
dc.citation.startPage | 2326 | - |
dc.citation.title | MARINE DRUGS | - |
dc.citation.volume | 12 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Bae, Munhyung | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | sponge | - |
dc.subject.keywordAuthor | rare actinomycete | - |
dc.subject.keywordAuthor | Amycolatopsis | - |
dc.subject.keywordAuthor | benzofuran | - |
dc.subject.keywordAuthor | cyclopiazonic acid | - |
dc.subject.keywordPlus | MARINE | - |
dc.subject.keywordPlus | BIOSYNTHESIS | - |
dc.subject.keywordPlus | ANTIBIOTICS | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | POLYKETIDE | - |
dc.subject.keywordPlus | METABOLITE | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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