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New diterpenoids from the stems of Euphorbia antiquorum growing in Vietnam

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dc.contributor.authorTran, T.-N.-
dc.contributor.authorSichaem, J.-
dc.contributor.authorNguyen, V.-K.-
dc.contributor.authorNguyen, H.-H.-
dc.contributor.authorCao, T.-T.-
dc.contributor.authorNguyen, T.-P.-
dc.contributor.authorVo, V.-G.-
dc.contributor.authorNiamnont, N.-
dc.contributor.authorNguyen, N.-H.-
dc.contributor.authorDuong, T.-H.-
dc.date.accessioned2022-01-22T02:40:09Z-
dc.date.available2022-01-22T02:40:09Z-
dc.date.created2020-07-20-
dc.date.issued2022-01-
dc.identifier.issn1478-6419-
dc.identifier.urihttps://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83338-
dc.description.abstractPhytochemical analysis of Euphorbia antiquorum stem extracts afforded two new ent-atisane compounds, ent-3α-acetoxy-16β,17,18-trihydroxyatisane (1) and ent-3α,14,16β,17-tetrahydroxyatisane (2) together with three known compounds, 20-deoxy-16-hydroxyingenol (3), ent-14[S],16α,17-trihydroxyatisan-3-one (4), and agallochaol C (5). Their structures were elucidated by spectroscopic data analysis and comparison with published NMR data. Compounds 1–5 were evaluated for α-glucosidase inhibition and cytotoxicity. Compounds 1, 4, and 5 revealed significant inhibitory activity against α-glucosidase with the IC50 values of 119.9, 135.5, and 134.3 µM, respectively. None showed activity in cytotoxicity assay. © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group.-
dc.language영어-
dc.language.isoen-
dc.publisherTAYLOR & FRANCIS LTD-
dc.relation.isPartOfNatural Product Research-
dc.titleNew diterpenoids from the stems of Euphorbia antiquorum growing in Vietnam-
dc.typeArticle-
dc.type.rimsART-
dc.description.journalClass1-
dc.identifier.wosid000547024900001-
dc.identifier.doi10.1080/14786419.2020.1789634-
dc.identifier.bibliographicCitationNatural Product Research, v.36, no.2, pp.1 - 8-
dc.description.isOpenAccessN-
dc.identifier.scopusid2-s2.0-85087828483-
dc.citation.endPage8-
dc.citation.startPage1-
dc.citation.titleNatural Product Research-
dc.citation.volume36-
dc.citation.number2-
dc.contributor.affiliatedAuthorVo, V.-G.-
dc.type.docTypeArticle-
dc.subject.keywordAuthorent-atisane diterpenoid-
dc.subject.keywordAuthorEuphorbia antiquorum L-
dc.subject.keywordAuthorEuphorbiaceae-
dc.subject.keywordAuthorα-glucosidase inhibition-
dc.subject.keywordPlusINGOL-TYPE DITERPENES-
dc.subject.keywordPlusALPHA-GLUCOSIDASE-
dc.subject.keywordPlusPLANTS-
dc.subject.keywordPlusLATEX-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalWebOfScienceCategoryChemistry, Applied-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
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산업·환경대학원 > 산업환경공학과 > 1. Journal Articles

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