New diterpenoids from the stems of Euphorbia antiquorum growing in Vietnam
DC Field | Value | Language |
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dc.contributor.author | Tran, T.-N. | - |
dc.contributor.author | Sichaem, J. | - |
dc.contributor.author | Nguyen, V.-K. | - |
dc.contributor.author | Nguyen, H.-H. | - |
dc.contributor.author | Cao, T.-T. | - |
dc.contributor.author | Nguyen, T.-P. | - |
dc.contributor.author | Vo, V.-G. | - |
dc.contributor.author | Niamnont, N. | - |
dc.contributor.author | Nguyen, N.-H. | - |
dc.contributor.author | Duong, T.-H. | - |
dc.date.accessioned | 2022-01-22T02:40:09Z | - |
dc.date.available | 2022-01-22T02:40:09Z | - |
dc.date.created | 2020-07-20 | - |
dc.date.issued | 2022-01 | - |
dc.identifier.issn | 1478-6419 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83338 | - |
dc.description.abstract | Phytochemical analysis of Euphorbia antiquorum stem extracts afforded two new ent-atisane compounds, ent-3α-acetoxy-16β,17,18-trihydroxyatisane (1) and ent-3α,14,16β,17-tetrahydroxyatisane (2) together with three known compounds, 20-deoxy-16-hydroxyingenol (3), ent-14[S],16α,17-trihydroxyatisan-3-one (4), and agallochaol C (5). Their structures were elucidated by spectroscopic data analysis and comparison with published NMR data. Compounds 1–5 were evaluated for α-glucosidase inhibition and cytotoxicity. Compounds 1, 4, and 5 revealed significant inhibitory activity against α-glucosidase with the IC50 values of 119.9, 135.5, and 134.3 µM, respectively. None showed activity in cytotoxicity assay. © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.relation.isPartOf | Natural Product Research | - |
dc.title | New diterpenoids from the stems of Euphorbia antiquorum growing in Vietnam | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000547024900001 | - |
dc.identifier.doi | 10.1080/14786419.2020.1789634 | - |
dc.identifier.bibliographicCitation | Natural Product Research, v.36, no.2, pp.1 - 8 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85087828483 | - |
dc.citation.endPage | 8 | - |
dc.citation.startPage | 1 | - |
dc.citation.title | Natural Product Research | - |
dc.citation.volume | 36 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Vo, V.-G. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | ent-atisane diterpenoid | - |
dc.subject.keywordAuthor | Euphorbia antiquorum L | - |
dc.subject.keywordAuthor | Euphorbiaceae | - |
dc.subject.keywordAuthor | α-glucosidase inhibition | - |
dc.subject.keywordPlus | INGOL-TYPE DITERPENES | - |
dc.subject.keywordPlus | ALPHA-GLUCOSIDASE | - |
dc.subject.keywordPlus | PLANTS | - |
dc.subject.keywordPlus | LATEX | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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