In vitro Anti-inflammatory Activities and Phenolic Acid Analysis of Tree Sprout Extracts
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김주리 | - |
dc.contributor.author | 퀸누구엔 | - |
dc.contributor.author | 신한나 | - |
dc.contributor.author | 강기성 | - |
dc.contributor.author | 이상현 | - |
dc.date.accessioned | 2022-01-28T01:40:46Z | - |
dc.date.available | 2022-01-28T01:40:46Z | - |
dc.date.created | 2021-12-31 | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 0253-3073 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83367 | - |
dc.description.abstract | This study evaluated several in vitro activities including the preliminary assessment of the anti-cancer, anti-inflammatory, and anti-diabetic effects of tree sprout extracts. Chlorogenic, caffeic, and p-coumaric acid contents in tree sprouts were analyzed using high-performance liquid chromatography and an ultraviolet detector. Among the studied tree sprout extracts, the ethanol (EtOH) extract of Rhus verniciflua exhibited the most potent anti-cancer effect by suppressing the cell viability of a human gastric adenocarcinoma cell line, with an IC50 of 7.06 µg/mL. The EtOH extract of Morus alba (MAB) inhibited the secretion of nitric oxide (NO) at a concentration of 100 µg/mL, with an IC50 of 83.44 µg/mL. Moreover, the EtOH extract of Securinega suffruticosa inhibited NO secretion with the lowest IC50 of 54.42 µg/mL. The EtOH extract of Fraxinus mandschurica was the only extract with effective α-glucosidase inhibitory activity. The total content of chlorogenic, caffeic, and p-coumaric acids was the highest in MAB (14.63 mg/g ext.). In conclusion, the beneficial activities of the tree sprout extracts with high phenolic acid content were generally high. Our results provide a theoretical basis for the development of health-promoting supplements and functional foods. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 한국생약학회 | - |
dc.relation.isPartOf | 생약학회지 | - |
dc.title | In vitro Anti-inflammatory Activities and Phenolic Acid Analysis of Tree Sprout Extracts | - |
dc.title.alternative | 수엽류 새순의 항염증 활성 및 페놀산 분석 | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.22889/KJP.2021.52.4.257 | - |
dc.identifier.bibliographicCitation | 생약학회지, v.52, no.4, pp.257 - 266 | - |
dc.identifier.kciid | ART002790488 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85123197378 | - |
dc.citation.endPage | 266 | - |
dc.citation.startPage | 257 | - |
dc.citation.title | 생약학회지 | - |
dc.citation.volume | 52 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | 퀸누구엔 | - |
dc.contributor.affiliatedAuthor | 강기성 | - |
dc.subject.keywordAuthor | Anti-cancer | - |
dc.subject.keywordAuthor | Anti-inflammatory | - |
dc.subject.keywordAuthor | Anti-diabetes | - |
dc.subject.keywordAuthor | Phenolic acid | - |
dc.subject.keywordAuthor | Tree sprout | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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