The Impact of Air Pollutants and Meteorological Factors on Chronic Obstructive Pulmonary Disease Exacerbations: A Nationwide Study
DC Field | Value | Language |
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dc.contributor.author | Huh, Jin-Young | - |
dc.contributor.author | Hong, Jinwook | - |
dc.contributor.author | Han, Dong-Woo | - |
dc.contributor.author | Park, Young-Jun | - |
dc.contributor.author | Jung, Jaehun | - |
dc.contributor.author | Lee, Sei Won | - |
dc.date.accessioned | 2022-02-20T02:40:17Z | - |
dc.date.available | 2022-02-20T02:40:17Z | - |
dc.date.created | 2022-02-10 | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 2325-6621 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83519 | - |
dc.description.abstract | Rationale: Chronic obstructive lung disease (COPD) is a chronic progressive disease. Although smoking is the most important risk factor, 30% of patients with COPD are never-smokers, and environmental agents are also influential. The effects of air pollutants and meteorological factors on COPD exacerbations have not been studied extensively. Objectives: We aimed to investigate the air pollutants and meteorological factors that impact the incidence of COPD exacerbations. Methods: We obtained clinical data of COPD exacerbation cases from The National Health Insurance Service and merged it with 24-hour average values of air pollutants and meteorological factors from national databases. Patients who reside in eight metropolitan cities, where observatory stations are densely located, were selected for analysis. Results: In 1,404,505 patients with COPD between 2013 and 2018, 15,282 COPD exacerbations leading to hospitalization or emergency room visits were identified. Among the various air pollutants and meteorological factors, particulate matter ⩽2.5 μm in aerodynamic diameter (PM2.5), particulate matter ⩽10 μm in aerodynamic diameter (PM10), NO2, SO2, CO, O3, average temperature, and diurnal temperature range (DTR) were associated with COPD exacerbations. Generalized additive mode model analysis with cubic splines showed an inverted U-shaped relationship with PM2.5, PM10, CO, NO2, SO2, O3, DTR, and humidity, whereas it displayed a U-shaped pattern with the average temperature. Distinct patterns were found from 2015-2016 to 2017-2018. Conclusions: PM2.5, PM10, CO, NO2, O3, SO2, average temperature, humidity, and DTR affected the incidence of COPD exacerbations in various patterns, up to 10 lag days. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER THORACIC SOC | - |
dc.relation.isPartOf | Annals of the American Thoracic Society | - |
dc.title | The Impact of Air Pollutants and Meteorological Factors on Chronic Obstructive Pulmonary Disease Exacerbations: A Nationwide Study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000752423600013 | - |
dc.identifier.doi | 10.1513/AnnalsATS.202103-298OC | - |
dc.identifier.bibliographicCitation | Annals of the American Thoracic Society, v.19, no.2, pp.214 - 226 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85123968474 | - |
dc.citation.endPage | 226 | - |
dc.citation.startPage | 214 | - |
dc.citation.title | Annals of the American Thoracic Society | - |
dc.citation.volume | 19 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Hong, Jinwook | - |
dc.contributor.affiliatedAuthor | Jung, Jaehun | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | air pollutants | - |
dc.subject.keywordAuthor | COPD | - |
dc.subject.keywordAuthor | meteorology | - |
dc.subject.keywordAuthor | particulate matter | - |
dc.subject.keywordPlus | DIURNAL TEMPERATURE-RANGE | - |
dc.subject.keywordPlus | LONG-TERM EXPOSURE | - |
dc.subject.keywordPlus | PARTICULATE MATTER | - |
dc.subject.keywordPlus | NEVER-SMOKERS | - |
dc.subject.keywordPlus | LUNG-FUNCTION | - |
dc.subject.keywordPlus | COPD | - |
dc.subject.keywordPlus | POLLUTION | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | HOSPITALIZATIONS | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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