Coordinated regulation of interferon and inflammasome signaling pathways by SARS-CoV-2 proteins
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Na-Eun | - |
dc.contributor.author | Song, Yoon-Jae | - |
dc.date.accessioned | 2022-02-28T07:40:22Z | - |
dc.date.available | 2022-02-28T07:40:22Z | - |
dc.date.created | 2022-02-05 | - |
dc.date.issued | 2022-03 | - |
dc.identifier.issn | 1225-8873 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83589 | - |
dc.description.abstract | Type I and III interferons (IFNs) and the nucleotide-binding domain (NBD) leucine-rich repeat (LRR)-containing receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome play pivotal roles in the pathogenesis of SARS-CoV-2. While optimal IFN and inflammasome responses are essential for limiting SARS-CoV-2 infection, aberrant activation of these innate immune responses is associated with COVID-19 pathogenesis. In this review, we focus our discussion on recent findings on SARS-CoV-2-induced type I and III IFNs and NLRP3 inflammasome responses and the viral proteins regulating these mechanisms. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MICROBIOLOGICAL SOCIETY KOREA | - |
dc.relation.isPartOf | JOURNAL OF MICROBIOLOGY | - |
dc.title | Coordinated regulation of interferon and inflammasome signaling pathways by SARS-CoV-2 proteins | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000748166700003 | - |
dc.identifier.doi | 10.1007/s12275-022-1502-8 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY, v.60, no.3, pp.300 - 307 | - |
dc.identifier.kciid | ART002813843 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85123826688 | - |
dc.citation.endPage | 307 | - |
dc.citation.startPage | 300 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY | - |
dc.citation.volume | 60 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Kim, Na-Eun | - |
dc.contributor.affiliatedAuthor | Song, Yoon-Jae | - |
dc.type.docType | Review; Early Access | - |
dc.subject.keywordAuthor | inflammasome | - |
dc.subject.keywordAuthor | interferon | - |
dc.subject.keywordAuthor | severe acute respiratory syndrome corona virus 2 | - |
dc.subject.keywordPlus | HOST GENE-EXPRESSION | - |
dc.subject.keywordPlus | I INTERFERON | - |
dc.subject.keywordPlus | NSP1 | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | PROTEASE | - |
dc.subject.keywordPlus | IMMUNITY | - |
dc.subject.keywordPlus | REVEALS | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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