Rare Case of Anal Canal Signet Ring Cell Carcinoma Associated with Perianal and Vulvar Pagetoid Spread
- Authors
- Kim, Na Rae; Cho, Hyun Yee; Baek, Jeong-Heum; Jeong, Juhyeon; Ha, Seung Yeon; Seok, Jae Yeon; Park, Sung Won; Sym, Sun Jin; Lee, Kyu Chan; Chung, Dong Hae
- Issue Date
- May-2016
- Publisher
- KOREAN SOC PATHOLOGISTS
- Keywords
- Carcinoma; signet ring cell; Anal canal; Paget disease; extramammary
- Citation
- JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE, v.50, no.3, pp.231 - 237
- Journal Title
- JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE
- Volume
- 50
- Number
- 3
- Start Page
- 231
- End Page
- 237
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8360
- DOI
- 10.4132/jptm.2015.08.08
- ISSN
- 2383-7837
- Abstract
- A 61-year-old woman was referred to surgery for incidentally found colonic polyps during a health examination. Physical examination revealed widespread eczematous skin lesion without pruritus in the perianal and vulvar area. Abdominopelvic computed tomography showed an approximately 4-cm-sized, soft tissue lesion in the right perianal area. Inguinal lymph node dissection and Mils' operation extended to perianal and perivulvar skin was performed. Histologically, the anal canal lesion was composed of mucin-containing signet ring cells, which were similar to those found in Pagetoid skin lesions. It was diagnosed as an anal canal signet ring cell carcinoma (SRCC) with perianal and vulvar Pagetoid spread and bilateral inguinal lymph node metastasis. Anal canal SRCC is rare, and the current case is the third reported case in the English literature. Seven additional cases were retrieved from the world literature. Here, we describe this rare case of anal canal SRCC with perianal Pagetoid spread and provide a literature review.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 의과대학 > 의학과 > 1. Journal Articles
- 의과대학 > 의예과 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.