Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma in Korea
DC Field | Value | Language |
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dc.contributor.author | Kim, J.M. | - |
dc.contributor.author | Joo, D.J. | - |
dc.contributor.author | Hwang, S. | - |
dc.contributor.author | Yi, N.-J. | - |
dc.contributor.author | Ryu, J.H. | - |
dc.contributor.author | Na, Y.W. | - |
dc.contributor.author | Kim, D.-S. | - |
dc.contributor.author | Kim, D.J. | - |
dc.contributor.author | Yoo, Y.K. | - |
dc.contributor.author | Yu, H.C. | - |
dc.contributor.author | Kim, M.S. | - |
dc.date.accessioned | 2022-03-22T05:40:07Z | - |
dc.date.available | 2022-03-22T05:40:07Z | - |
dc.date.created | 2021-10-02 | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 2508-5778 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83791 | - |
dc.description.abstract | Introduction: There is still no consensus about the actual role of liver transplantation (LT) in the therapeutic algorithm of combined hepatocellular-cholangiocarcinoma (cHCC-CC) because of low incidence and few clinical information. Methods: We retrospectively identified 111 patients at nine centers from 2001 to 2019 in Korea. Results: Of the 111 patients, 85.6% (n = 95) was male and the median age was 54 years (range, 31–66 years). HBV is 82% (n = 91) and HCC is 96% (86.3%) preoperatively. Seventy-four patients (66.7%) received locoregional therapy (LRT) before LT. Median tumor size was 2.5 cm (range, 0.5–7.2 cm) and the ratio of beyond Milan criteria was 40.5% (n = 45). The 1-year, 3-year, and 5-year disease-free survival rates and tumor-related patient survival rates were 77.6%, 56.3%, and 51.1% and 84.4%, 63.8%, and 56.7%, respectively. The extrahepatic site was 75.5% as an initial tumor recurrence site in recurrent tumor patients. Numbers of LRT before LT >3 and tumor size > 3 cm were closely associated tumor recurrence and early tumor recurrence within 1 year after LT. Tumor size > 3 cm was only predisposing factor for tumor-related death. Conclusions: It is difficult to diagnose cHCC-CC before LT, but a good prognosis can be expected if the tumor size is less than 3 cm in pathology. © The Korean Association of Hepato-Biliary-Pancreatic Surgery. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Association of Hepato-Biliary-Pancreatic Surgery | - |
dc.relation.isPartOf | Annals of Hepato-Biliary-Pancreatic Surgery | - |
dc.title | Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma in Korea | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.14701/ahbps.LV-OP-2-5 | - |
dc.identifier.bibliographicCitation | Annals of Hepato-Biliary-Pancreatic Surgery, v.25, pp.S57 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85115738886 | - |
dc.citation.startPage | S57 | - |
dc.citation.title | Annals of Hepato-Biliary-Pancreatic Surgery | - |
dc.citation.volume | 25 | - |
dc.contributor.affiliatedAuthor | Kim, D.J. | - |
dc.type.docType | Note | - |
dc.description.journalRegisteredClass | other | - |
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