Preparation of Chitosan-Gold and Chitosan-Silver Nanodrug Carrier Using QDs
- Authors
- Lee, Yong-Choon; Kang, Ik-Joong
- Issue Date
- Apr-2016
- Publisher
- KOREAN INSTITUTE CHEMICAL ENGINEERS
- Keywords
- Chitosan-gold and Chitosan-silver Nanoshell; Quantum-Dots; Nanodrug Carrier
- Citation
- KOREAN CHEMICAL ENGINEERING RESEARCH, v.54, no.2, pp.200 - 205
- Journal Title
- KOREAN CHEMICAL ENGINEERING RESEARCH
- Volume
- 54
- Number
- 2
- Start Page
- 200
- End Page
- 205
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8402
- DOI
- 10.9713/kcer.2016.54.2.200
- ISSN
- 0304-128X
- Abstract
- A drug transport carrier could be used for safe send of drugs to the affected region in a human body. The chitosan is adequate for the drug delivery carrier because of adaptable to living body. The gold, a metallic nanoparticles, tends to form a nano complex at rapidly when it combined with chitosan because of its negative charge. having energy from the other, outer gold nano-complex make heat due to its property to release the contained drugs to the target area. Silver could be also formed an useful biocompatible nano-composites with chitosan which should be used as an useful drug transfer carrier because its special ability to protect microbial contamination. Being one of the oxidized nano metals, Fe3O4 is nontoxic and has been used for its magnetic characteristics. In this study, the control of catalyst, reducing agent, and solvent amount. The chitosan-Fe3O4-gold & silver nanoshell have been changed to form about 100 nm size by ionic bond between the amine group, an end group of chitosan, and the metal. It was observed the change in order to seek for its optimum reaction condition as a drug transfer carrier.
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Collections - 공과대학 > 화공생명공학과 > 1. Journal Articles
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