류마티스관절염 치료에서 오메가-3 다가불포화지방산의 역할
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 조의상 | - |
dc.contributor.author | 최경희 | - |
dc.date.accessioned | 2022-04-30T09:40:06Z | - |
dc.date.available | 2022-04-30T09:40:06Z | - |
dc.date.created | 2022-04-30 | - |
dc.date.issued | 2016-11 | - |
dc.identifier.issn | 1226-640X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84177 | - |
dc.description.abstract | Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown cause. It is characterized by polyarthritis. Currently, treatments for RA include the use of non-steroidal antiinflammatory drugs (NSAIDs), steroid, disease-modifying antirheumatic drugs (DMARDs), corticosteroid, and so on. New treatment options for RA have been actively developed. In this study, we determined pharmacological advantages of using omega n-3 polyunsaturated fatty acids (PUFAs) as adjunctive therapy in RA based on articles demonstrating the role of omega n-3 in the prevention and treatment of RA. Omega n-3 PUFAs can partially suppress a number of inflammatory reactions such as leukocyte chemotaxis and adhesion molecule expression. Mechanisms fundamental to the anti-inflammatory actions of omega n-3 PUFAs involve changing the compositions of cell membrane's phospholipid fatty acids. Omega n-3 PUFAs with inflammation control action may also result in the reduction of pain in rheumatoid arthritis. The benefit of n-3 PUFAs in RA has also been suggested in some clinical studies. In conclusion, omega n-3 PUFAs might be useful as an adjuvant therapy for the treatment of RA. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 한국병원약사회 | - |
dc.relation.isPartOf | 병원약사회지 | - |
dc.title | 류마티스관절염 치료에서 오메가-3 다가불포화지방산의 역할 | - |
dc.title.alternative | Potential Role of Omega n-3 Polyunsaturated Fatty Acids and Its Use in Rheumatoid Arthritis | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.doi | 10.32429/jkshp.2016.33.4.005 | - |
dc.identifier.bibliographicCitation | 병원약사회지, v.33, no.4, pp.367 - 379 | - |
dc.identifier.kciid | ART002167829 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 379 | - |
dc.citation.startPage | 367 | - |
dc.citation.title | 병원약사회지 | - |
dc.citation.volume | 33 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | 최경희 | - |
dc.subject.keywordAuthor | Rheumatoid arthritis | - |
dc.subject.keywordAuthor | Omega n-3 polyunsaturated fatty acids | - |
dc.subject.keywordAuthor | Anti-inflammation effect | - |
dc.subject.keywordAuthor | Pain control | - |
dc.description.journalRegisteredClass | kci | - |
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