Efficacy and safety of temperature-controlled intraductal radiofrequency ablation in advanced malignant hilar biliary obstruction: A pilot multicenter randomized comparative trial
DC Field | Value | Language |
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dc.contributor.author | Kang, Huapyong | - |
dc.contributor.author | Han, Sung Yong | - |
dc.contributor.author | Cho, Jae Hee | - |
dc.contributor.author | Kim, Eui Joo | - |
dc.contributor.author | Kim, Dong Uk | - |
dc.contributor.author | Yang, Jae Kook | - |
dc.contributor.author | Jeon, Soyoung | - |
dc.contributor.author | Park, Goeun | - |
dc.contributor.author | Lee, Tae Hoon | - |
dc.date.accessioned | 2022-05-07T04:40:05Z | - |
dc.date.available | 2022-05-07T04:40:05Z | - |
dc.date.created | 2021-12-10 | - |
dc.date.issued | 2022-04 | - |
dc.identifier.issn | 1868-6974 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84203 | - |
dc.description.abstract | Purpose We aimed to evaluate the efficacy and safety of temperature-controlled intraductal radiofrequency ablation (ID-RFA) for advanced malignant hilar biliary obstruction (MHBO). Methods Patients were randomly assigned to RFA group (ID-RFA and bilateral plastic stent [PS]) or non-RFA group (bilateral PS) at a 1:1 ratio. Exchange to self-expanding metal stent (SEMS) was performed after 3 months or when premature PS occlusion occurred. Total event-free stent patency, overall survival (OS), and adverse events (AEs) were analyzed. Results A total of 30 patients from three hospitals were enrolled. Stent patency and OS did not differ between the two groups (178 days vs 122 days, P = .154; 230 days vs 144 days, P = .643; respectively). In patients with each stricture length >= 11 mm on both sides, stent patency was longer in the RFA group than in the non-RFA group (175 days vs 121 days, P = .028). More patients received elective exchange to SEMS without PS occlusion in the RFA group than in the non-RFA group (69.2% vs 23.1%, P = .018). AE rates did not differ between the two groups. Conclusions Temperature-controlled ID-RFA for advanced MHBO was safe and feasible. It could prevent premature PS occlusion within 3 months. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.relation.isPartOf | JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES | - |
dc.title | Efficacy and safety of temperature-controlled intraductal radiofrequency ablation in advanced malignant hilar biliary obstruction: A pilot multicenter randomized comparative trial | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000726294700001 | - |
dc.identifier.doi | 10.1002/jhbp.1082 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, v.29, no.4, pp.469 - 478 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85120489846 | - |
dc.citation.endPage | 478 | - |
dc.citation.startPage | 469 | - |
dc.citation.title | JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES | - |
dc.citation.volume | 29 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Kang, Huapyong | - |
dc.contributor.affiliatedAuthor | Kim, Eui Joo | - |
dc.type.docType | Article; Early Access | - |
dc.subject.keywordAuthor | cholangiocarcinoma | - |
dc.subject.keywordAuthor | cholangiopancreatography | - |
dc.subject.keywordAuthor | cholestasis | - |
dc.subject.keywordAuthor | endoscopic retrograde | - |
dc.subject.keywordAuthor | gallbladder neoplasms | - |
dc.subject.keywordAuthor | radiofrequency ablation | - |
dc.subject.keywordPlus | SAMPLE-SIZE | - |
dc.subject.keywordPlus | CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | STENTS | - |
dc.subject.keywordPlus | METAL | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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