Chemoselective Cu-catalyzed synthesis of diverse N-arylindole carboxamides, beta-oxo amides and N-arylindole-3-carbonitriles using diaryliodonium salts
DC Field | Value | Language |
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dc.contributor.author | Mehra, Manish Kumar | - |
dc.contributor.author | Malik, Monika | - |
dc.contributor.author | Kumar, Bintu | - |
dc.contributor.author | Kumar, Dalip | - |
dc.date.accessioned | 2022-06-09T08:40:15Z | - |
dc.date.available | 2022-06-09T08:40:15Z | - |
dc.date.created | 2022-06-09 | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 1477-0520 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84574 | - |
dc.description.abstract | Chemoselective copper-catalyzed synthesis of diverse N-arylindole-3-carboxamides, beta-oxo amides and N-arylindole-3-carbonitriles from readily accessible indole-3-carbonitriles, alpha-cyano ketones and diaryliodonium salts has been developed. Diverse N-arylindole-3-carboxamides and beta-oxo amides were successfully achieved in high yields under copper-catalyzed neutral reaction conditions, and the addition of an organic base (DIPEA) resulted in a completely different selectivity pattern to produce N-arylindole-3-carbonitriles. Moreover, the importance of the developed methodology was realized by the synthesis of indoloquinolones and N-((1H-indol-3-yl)methyl)aniline and by a single-step gram-scale synthesis of the naturally occurring cephalandole A analogue. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.relation.isPartOf | ORGANIC & BIOMOLECULAR CHEMISTRY | - |
dc.title | Chemoselective Cu-catalyzed synthesis of diverse N-arylindole carboxamides, beta-oxo amides and N-arylindole-3-carbonitriles using diaryliodonium salts | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000617008600017 | - |
dc.identifier.doi | 10.1039/d0ob02247k | - |
dc.identifier.bibliographicCitation | ORGANIC & BIOMOLECULAR CHEMISTRY, v.19, no.5, pp.1109 - 1114 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 1114 | - |
dc.citation.startPage | 1109 | - |
dc.citation.title | ORGANIC & BIOMOLECULAR CHEMISTRY | - |
dc.citation.volume | 19 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Mehra, Manish Kumar | - |
dc.type.docType | Article | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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