Practical one-pot amidation of N-Alloc-, N-Boc-, and N-Cbz protected amines under mild conditions
DC Field | Value | Language |
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dc.contributor.author | Van Hieu Tran | - |
dc.contributor.author | Kim, Hee-Kwon | - |
dc.contributor.author | Hong, Wan Pyo | - |
dc.date.accessioned | 2022-06-09T11:40:07Z | - |
dc.date.available | 2022-06-09T11:40:07Z | - |
dc.date.created | 2022-06-09 | - |
dc.date.issued | 2021-05 | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84584 | - |
dc.description.abstract | A facile one-pot synthesis of amides from N-Alloc-, N-Boc-, and N-Cbz-protected amines has been described. The reactions involve the use of isocyanate intermediates, which are generated in situ in the presence of 2-chloropyridine and trifluoromethanesulfonyl anhydride, to react with Grignard reagents to produce the corresponding amides. Using this reaction protocol, a variety of N-Alloc-, N-Boc-, and N-Cbz-protected aliphatic amines and aryl amines were efficiently converted to amides with high yields. This method is highly effective for the synthesis of amides and offers a promising approach for facile amidation. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.relation.isPartOf | RSC ADVANCES | - |
dc.title | Practical one-pot amidation of N-Alloc-, N-Boc-, and N-Cbz protected amines under mild conditions | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000649193500041 | - |
dc.identifier.doi | 10.1039/d1ra02242c | - |
dc.identifier.bibliographicCitation | RSC ADVANCES, v.11, no.26, pp.15890 - 15895 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85105716497 | - |
dc.citation.endPage | 15895 | - |
dc.citation.startPage | 15890 | - |
dc.citation.title | RSC ADVANCES | - |
dc.citation.volume | 11 | - |
dc.citation.number | 26 | - |
dc.contributor.affiliatedAuthor | Hong, Wan Pyo | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | THIO ACIDS | - |
dc.subject.keywordPlus | INHIBITORS | - |
dc.subject.keywordPlus | LIGATION | - |
dc.subject.keywordPlus | AMIDES | - |
dc.subject.keywordPlus | AZIDES | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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