Elevated On-Treatment Diastolic Blood Pressure and Cardiovascular Outcomes in the Presence of Achieved Systolic Blood Pressure Targets
DC Field | Value | Language |
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dc.contributor.author | Kim, D.-H. | - |
dc.contributor.author | Cho, I.-J. | - |
dc.contributor.author | Kim, W. | - |
dc.contributor.author | Lee, C.J. | - |
dc.contributor.author | Kim, H.-C. | - |
dc.contributor.author | Shin, J.-H. | - |
dc.contributor.author | Kang, S.-H. | - |
dc.contributor.author | Jung, M.-H. | - |
dc.contributor.author | Kwon, C.H. | - |
dc.contributor.author | Lee, J.-H. | - |
dc.contributor.author | Kim, H.L. | - |
dc.contributor.author | Kim, H.M. | - |
dc.contributor.author | Cho, I. | - |
dc.contributor.author | Kang, D.R. | - |
dc.contributor.author | Lee, H.-Y. | - |
dc.contributor.author | Chung, W.-J. | - |
dc.contributor.author | Kim, K.I. | - |
dc.contributor.author | Cho, E.J. | - |
dc.contributor.author | Sohn, I.-S. | - |
dc.contributor.author | Park, S. | - |
dc.contributor.author | Shin, J. | - |
dc.contributor.author | Ryu, S.K. | - |
dc.contributor.author | Kang, S.-M. | - |
dc.contributor.author | Pyun, W.B. | - |
dc.contributor.author | Cho, M.-C. | - |
dc.contributor.author | Kim, J.H. | - |
dc.contributor.author | Lee, J.H. | - |
dc.contributor.author | Ihm, S.-H. | - |
dc.contributor.author | Sung, K.-C. | - |
dc.date.accessioned | 2022-06-23T05:40:18Z | - |
dc.date.available | 2022-06-23T05:40:18Z | - |
dc.date.created | 2022-05-13 | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 1738-5520 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84755 | - |
dc.description.abstract | Background and Objectives: This study aimed to investigate the association between cardiovascular events and 2 different levels of elevated on-treatment diastolic blood pressures (DBP) in the presence of achieved systolic blood pressure targets (SBP). Methods: A nation-wide population-based cohort study comprised 237,592 patients with hypertension treated. The primary endpoint was a composite of cardiovascular death, myocardial infarction, and stroke. Elevated DBP was defined according to the Seventh Report of Joint National Committee (JNC7; SBP <140 mmHg, DBP ≥90 mmHg) or to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) definitions (SBP <130 mmHg, DBP ≥80 mmHg). Results: During a median follow-up of 9 years, elevated on-treatment DBP by the JNC7 definition was associated with an increased risk of the occurrence of primary endpoint compared with achieved both SBP and DBP (adjusted hazard ratio [aHR], 1.14; 95% confidence interval [CI], 1.05-1.24) but not in those by the 2017 ACC/AHA definition. Elevated on-treatment DBP by the JNC7 definition was associated with a higher risk of cardiovascular mortality (aHR, 1.42; 95% CI, 1.18-1.70) and stroke (aHR, 1.19; 95% CI, 1.08-1.30). Elevated on-treatment DBP by the 2017 ACC/AHA definition was only associated with stroke (aHR, 1.10; 95% CI, 1.04-1.16). Similar results were seen in the propensity-score-matched cohort. Conclusion: Elevated on-treatment DBP by the JNC7 definition was associated a high risk of major cardiovascular events, while elevated DBP by the 2017 ACC/AHA definition was only associated with a higher risk of stroke. The result of study can provide evidence of DBP targets in subjects who achieved SBP targets. © 2022 Korean Society of Circulation. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Society of Circulation | - |
dc.relation.isPartOf | Korean Circulation Journal | - |
dc.title | Elevated On-Treatment Diastolic Blood Pressure and Cardiovascular Outcomes in the Presence of Achieved Systolic Blood Pressure Targets | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000810362600007 | - |
dc.identifier.doi | 10.4070/kcj.2021.0330 | - |
dc.identifier.bibliographicCitation | Korean Circulation Journal, v.52, no.6, pp.460 - 474 | - |
dc.identifier.kciid | ART002843972 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85127025962 | - |
dc.citation.endPage | 474 | - |
dc.citation.startPage | 460 | - |
dc.citation.title | Korean Circulation Journal | - |
dc.citation.volume | 52 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Chung, W.-J. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Blood pressure | - |
dc.subject.keywordAuthor | Hypertension | - |
dc.subject.keywordPlus | CORONARY-HEART-DISEASE | - |
dc.subject.keywordPlus | YOUNG ADULTHOOD | - |
dc.subject.keywordPlus | HYPERTENSION | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | GUIDELINE | - |
dc.subject.keywordPlus | STROKE | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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