Substrate or Solvent-Controlled Pd-II-Catalyzed Regioselective Arylation of Quinolin-4(1H)-ones Using Diaryliodonium Salts: Facile Access to Benzoxocine and Aaptamine Analogues
DC Field | Value | Language |
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dc.contributor.author | Mehra, Manish K. | - |
dc.contributor.author | Sharma, Shivani | - |
dc.contributor.author | Rangan, Krishnan | - |
dc.contributor.author | Kumar, Dalip | - |
dc.date.accessioned | 2022-06-23T07:40:05Z | - |
dc.date.available | 2022-06-23T07:40:05Z | - |
dc.date.created | 2022-06-23 | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 1434-193X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/84765 | - |
dc.description.abstract | Regioselective C3, C5, and C8 arylation of quinolin-4(1H)-ones have been accomplished either by substrate-control or by tuning the reaction solvent. A variety of aryl(mesityl)iodonium triflates could smoothly deliver arylated products in good to excellent yields. Additionally, it offers great flexibility by arylating medicinally potent quinolone related heterocycles such as acridin-9(10H)-one, and phenanthridin-6(5H)-one under standard reaction conditions. This strategy was further extended with diphenyleneiodonium triflate to access oxacine fused quinolines. The post-modifications of synthesized products enhance the further utility of this protocol in organic synthesis. To the best of our knowledge, this is the first report on C5 arylation of quinolin-4(1H)-ones using iodine(III) reagents. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.relation.isPartOf | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | - |
dc.title | Substrate or Solvent-Controlled Pd-II-Catalyzed Regioselective Arylation of Quinolin-4(1H)-ones Using Diaryliodonium Salts: Facile Access to Benzoxocine and Aaptamine Analogues | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000528914600012 | - |
dc.identifier.doi | 10.1002/ejoc.202000013 | - |
dc.identifier.bibliographicCitation | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, v.2020, no.16, pp.2409 - 2413 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85081344182 | - |
dc.citation.endPage | 2413 | - |
dc.citation.startPage | 2409 | - |
dc.citation.title | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | - |
dc.citation.volume | 2020 | - |
dc.citation.number | 16 | - |
dc.contributor.affiliatedAuthor | Mehra, Manish K. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | C-H functionalization | - |
dc.subject.keywordAuthor | Quinolin-4(1H)-one | - |
dc.subject.keywordAuthor | Diaryliodonium salts | - |
dc.subject.keywordAuthor | Palladium catalyst | - |
dc.subject.keywordAuthor | Regioselectivety | - |
dc.subject.keywordPlus | C-H ARYLATION | - |
dc.subject.keywordPlus | CYCLIC DIARYLIODONIUM | - |
dc.subject.keywordPlus | ANTIMALARIAL ACTIVITY | - |
dc.subject.keywordPlus | DIRECTING GROUP | - |
dc.subject.keywordPlus | ISOCRYPTOLEPINE | - |
dc.subject.keywordPlus | ALKALOIDS | - |
dc.subject.keywordPlus | NITROGEN | - |
dc.subject.keywordPlus | FUNCTIONALIZATION | - |
dc.subject.keywordPlus | HETEROCYCLES | - |
dc.subject.keywordPlus | REACTIVITY | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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