Review-Electrochemical Aptasensor for Pathogenic Bacteria Detection

Abstract

Pathogenic bacteria are a major public cause of foodborne and waterborne infections and are currently among the most serious public health threats. Conventional diagnostic techniques for bacteria, including plate culturing, the polymerase chain reaction, and the enzyme-linked immunosorbent assay, have many limitations, such as time consumption, high rates of false results, and complex instrument requirements. Aptamer-based electrochemical biosensors for bacteria address several of these issues and are promising for bacterial detection. This review discusses the current advances in electrochemical aptasensors for pathogenic bacteria with regard to the sensing performance with various specific aptamers for different types of bacteria. The advantages and disadvantages of these electrochemical aptasensors were investigated with the aim of promoting the development and commercialization of electrochemical aptasensors for the point-of-care detection of bacteria.