An experimental study on the Ag-MgAC-MIL-53(Fe)-based electrochemical sensing electrode for monitoring chloromycetin

Abstract

A simple and efficient electroactive modification matrix of silver nanoparticles (AgNPs), Mg-aminoclay (MgAC), and Materials of Institute Lavoisier (MIL)–53(Fe) was evaluated for an electrochemical sensor. The morphology, structure, and characterization of the proposed modification materials were assessed in detail using ultraviolet-visible light (UV-Vis) spectroscopy, X-ray powder diffraction, Raman spectroscopy, and transmission electron microscopy. The electrochemical properties and sensing performance of chloromycetin (CM), a broad-spectrum antibiotic drug that has numerous adverse effects, at the modified electrodes were measured using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Benefiting from possessing attractive chemical and physical properties, AgNPs synthesized from a simple reduction method were stabilized and homogeneously decorated on the MIL-53(Fe) framework owing to the presence of layered-MgAC nanomaterial, promising the increase in electrical conductivity, charge transferability, electrocatalytic activity, adsorption capability, and structural stability of the modified electrode (Ag-MgAC-MIL-53(Fe)/screen-printed electrode (SPE)). Under the optimized experimental condition, the concentration linear range was determined from 0.1–30 µM, corresponding to a rather low detection limit of 0.1 µM. This modified electrode had good repeatability, stability, and selectivity, demonstrating its high application potential in electrochemical sensors. © 2022 Elsevier B.V.