Plasma-Treated Flexible Aminoclay-Decorated Electrospun Nanofibers for Neural Stem Cell Self-Renewal
DC Field | Value | Language |
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dc.contributor.author | Lee, Young-Chul | - |
dc.contributor.author | Lee, Hyun Uk | - |
dc.contributor.author | Lee, Minhyung | - |
dc.contributor.author | Kim, Janghwan | - |
dc.contributor.author | Huh, Yun Suk | - |
dc.date.available | 2020-02-28T02:45:40Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2016-02 | - |
dc.identifier.issn | 1533-4880 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8595 | - |
dc.description.abstract | Biocompatible Mg- and Fe-aminoclays (MgAC and FeAC)-decorated polyacrylonitrile (PAN) nanofibers (NFs, diameter range: 190-380 nm) are prepared by the electrospinning process. There is a large increase in the biomolecular activities of the PAN NFs that were oxygen plasma (OP)-treated (the OPNFs) relative to those of the pristine PAN NFs, due to the OP treatment's carboxylation and/or hydroxylation of the PAN NF surfaces. With morphological observation by scanning electron microscopy (SEM), and following further confirmation of the Fourier-transform infrared (FI-IR) spectra of the as-prepared AC-OPNFs, human neural stem cell (NSC) self-renewal is tested, focusing on the relevant discrepancies among the AC-OPNFs, OPNFs, and pristine PAN NFs as flexible cellular matrices. Interestingly, NSCs are attached well on four NFs without conventional coating materials. Self-renewal of NSCs is confirmed by marker expressions such as PAX6 and N-CADHERIN. Among four NFs, FeAC-OPNFs shows the best property of NSC self-renewal. It is expected that AC-OPNFs can be xeno-free and protein-free extracellular matrices for supporting human NSC self-renewal. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER SCIENTIFIC PUBLISHERS | - |
dc.relation.isPartOf | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | - |
dc.subject | ATMOSPHERIC-PLASMA | - |
dc.subject | FE-AMINOCLAY | - |
dc.subject | MOLECULES | - |
dc.subject | FIBERS | - |
dc.title | Plasma-Treated Flexible Aminoclay-Decorated Electrospun Nanofibers for Neural Stem Cell Self-Renewal | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000372358800020 | - |
dc.identifier.doi | 10.1166/jnn.2016.11911 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.16, no.2, pp.1392 - 1395 | - |
dc.identifier.scopusid | 2-s2.0-84959346347 | - |
dc.citation.endPage | 1395 | - |
dc.citation.startPage | 1392 | - |
dc.citation.title | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | - |
dc.citation.volume | 16 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Lee, Young-Chul | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Electrospun Fiber | - |
dc.subject.keywordAuthor | Aminoclay | - |
dc.subject.keywordAuthor | Neural Stem Cell | - |
dc.subject.keywordAuthor | Self-Renewal | - |
dc.subject.keywordPlus | ATMOSPHERIC-PLASMA | - |
dc.subject.keywordPlus | FE-AMINOCLAY | - |
dc.subject.keywordPlus | MOLECULES | - |
dc.subject.keywordPlus | FIBERS | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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