Green nanoparticles as multifunctional nanomedicines: Insights into anti-inflammatory effects, growth signaling and apoptosis mechanism in cancer
- Authors
- Naseer, Faiza; Ahmed, Madiha; Majid, Abdul; Kamal, Warda; Phull, Abdul Rehman
- Issue Date
- Nov-2022
- Publisher
- ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
- Keywords
- Green nanoparticles; Nanomedicine; Cancer; Inflammation; Molecular mechanism; Autophagy
- Citation
- SEMINARS IN CANCER BIOLOGY, v.86, pp.310 - 324
- Journal Title
- SEMINARS IN CANCER BIOLOGY
- Volume
- 86
- Start Page
- 310
- End Page
- 324
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/86653
- DOI
- 10.1016/j.semcancer.2022.06.014
- ISSN
- 1044-579X
- Abstract
- Recently, green nanotechnology got great attention due to their reliable, sustainable, and eco-friendly synthesis protocols. The green nanoparticles (GNPs) are preferred over chemically synthesized nanoparticles owing to less destructive effects associated with the synthesis procedures as well as therapeutic involvement. In this review, we have discussed the applications of GNPs in inflammation-mediated disorders, with special emphasis on cancer, initiated due to oxidative stress and inflammatory cascade. Real-time mechanism based studies on GNPs have suggested their anticancer effects through inducing apoptosis, inhibiting angiogenesis, tissue invasion metastasis, reduced replicative capabilities in addition to target specific different signaling molecules and cascades involved in the development or progression of cancer. Moreover, the association of GNPs with the inhibition or induction of autophagy for the management of cancer has also been discussed. A large number of studies showed the GNPs have multifunctional biomedical properties of theranostic prominence. Therefore, the development of GNPs with naturally established systems could upsurge their definite applications as biomedicines including target specific destruction of the cancerous cells.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 바이오나노대학 > 식품생물공학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/86653)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.