Efficacy and Safety of 3 Versus 6 Months of Dual-Antiplatelet Therapy in Patients Implanted With Coroflex ISAR Stents: A Prospective, Multicenter, Randomized Clinical Trial
DC Field | Value | Language |
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dc.contributor.author | Jin, Uram | - |
dc.contributor.author | Seo, Kyoung-Woo | - |
dc.contributor.author | Yang, Hyoung-Mo | - |
dc.contributor.author | Lim, Hong-Seok | - |
dc.contributor.author | Choi, Byoung-Joo | - |
dc.contributor.author | Choi, So-Yeon | - |
dc.contributor.author | Shin, Joon-Han | - |
dc.contributor.author | Tahk, Seung-Jea | - |
dc.contributor.author | Yoo, Sang-Yong | - |
dc.contributor.author | Rha, Seung Woon | - |
dc.contributor.author | Chung, Woo-Young | - |
dc.contributor.author | Kim, Chi-Hoon | - |
dc.contributor.author | Won, Ki-Bum | - |
dc.contributor.author | Pyun, Wook Bum | - |
dc.contributor.author | Jang, Jae Sik | - |
dc.contributor.author | Lee, Sung Yun | - |
dc.contributor.author | Hong, Young Joon | - |
dc.contributor.author | Kim, Moo Hyun | - |
dc.contributor.author | Hong, Soon Jun | - |
dc.contributor.author | Choi, Yun-Seok | - |
dc.contributor.author | Kim, Hee-Yeol | - |
dc.contributor.author | Choi, Rak Kyeong | - |
dc.contributor.author | Kang, Woong Chol | - |
dc.contributor.author | Cho, Eun Joo | - |
dc.contributor.author | Yoon, Myeong-Ho | - |
dc.date.accessioned | 2023-01-19T00:40:39Z | - |
dc.date.available | 2023-01-19T00:40:39Z | - |
dc.date.created | 2023-01-18 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 1042-3931 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/86667 | - |
dc.description.abstract | Background. The optimal duration of dual-antiplatelet therapy (DAPT) after implantation of a drug-eluting stent (DES), especially recently developed polymer-free DESs, is unknown. This study examined the efficacy and safety of 3- versus 6-month DAPT in patients implanted with Coroflex ISAR polymer-free DESs. Methods. Between May 2015 and August 2020, 488 patients who underwent Coroflex ISAR stent implantation were enrolled in the study and randomly assigned to the 3-month (n=244) or 6-month (n=244) DAPT group. Results. At 1 year, the primary endpoint (composite of cardiovascular death, myocardial infarction, target vessel revascularization, and Bleeding Academic Research Consortium [BARC] type 2-5 bleeding) occurred in 9 (3.7%) patients in the 3-month DAPT group and in 7 (2.9%) patients in the 6-month DAPT group (hazard ratio, 1.31; P=.60). There was no difference between the 3- and 6-month DAPT groups in either BARC type 2-5 bleeding (1.6% vs 0.8%; hazard ratio, 2.00; P=.42) or any bleeding (2.9% vs 3.3%; hazard ratio, 0.87; P=.80). Conclusion. Compared with 6 months of DAPT, 3 months of DAPT did not increase the risk of primary endpoint 1 year after Coroflex ISAR stent implantation, although it should be noted that the trial has limited power to see differences due to low event rate and low recruitment rate. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | H M P COMMUNICATIONS | - |
dc.relation.isPartOf | JOURNAL OF INVASIVE CARDIOLOGY | - |
dc.title | Efficacy and Safety of 3 Versus 6 Months of Dual-Antiplatelet Therapy in Patients Implanted With Coroflex ISAR Stents: A Prospective, Multicenter, Randomized Clinical Trial | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000891637300002 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INVASIVE CARDIOLOGY, v.34, no.9, pp.E653 - E659 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | E659 | - |
dc.citation.startPage | E653 | - |
dc.citation.title | JOURNAL OF INVASIVE CARDIOLOGY | - |
dc.citation.volume | 34 | - |
dc.citation.number | 9 | - |
dc.contributor.affiliatedAuthor | Kang, Woong Chol | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | coronary artery disease | - |
dc.subject.keywordAuthor | drug-eluting stents | - |
dc.subject.keywordAuthor | dual-antiplatelet therapy | - |
dc.subject.keywordAuthor | duration of therapy | - |
dc.subject.keywordAuthor | randomized controlled trial | - |
dc.subject.keywordPlus | DRUG-ELUTING STENTS | - |
dc.subject.keywordPlus | ELEVATION MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | CORONARY-ARTERY-DISEASE | - |
dc.subject.keywordPlus | ASSOCIATION TASK-FORCE | - |
dc.subject.keywordPlus | POLYMER-FREE | - |
dc.subject.keywordPlus | FOCUSED UPDATE | - |
dc.subject.keywordPlus | BARE-METAL | - |
dc.subject.keywordPlus | DISCONTINUATION | - |
dc.subject.keywordPlus | COLLABORATION | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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