Interlinking brain mapping and Parkinson’s disease: MRI analysis, nigrosome 1 and nigrosome 4
DC Field | Value | Language |
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dc.contributor.author | Kim, Eung Yeop | - |
dc.contributor.author | Sung, Young Hee | - |
dc.contributor.author | Lee, Jongho | - |
dc.date.accessioned | 2023-02-14T08:40:14Z | - |
dc.date.available | 2023-02-14T08:40:14Z | - |
dc.date.created | 2023-02-14 | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0000-0000 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/86866 | - |
dc.description.abstract | The nigrosome 1 and 4 regions in the substantia nigra can be assessed separately by using high-spatial-resolution susceptibility map-weighted imaging. The nigrosome 1 region is mainly identified below the red nucleus, while the nigrosome 4 region is located at the level of the lower portion of the red nucleus on coronal-reformatted susceptibility map-weighted imaging. Each region exhibits differential involvement according to clinical stages in idiopathic Parkinson’s disease, with the nigrosome 1 region involved earlier, followed by the nigrosome 4 region. Such observations may be supported by coregistered high-spatial-resolution neuromelanin-sensitive imaging and the relationship with the extent of abnormality of dopamine transporter activity. From our results, we suggest that high-spatial-resolution susceptibility map-weighted imaging may serve not only as a diagnostic tool but also as an imaging biomarker for disease severity in idiopathic Parkinson’s disease. © 2020 Elsevier Inc. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | Genetics, Neurology, Behavior, and Diet in Parkinson’s Disease: The Neuroscience of Parkinson’s Disease, Volume 2 | - |
dc.title | Interlinking brain mapping and Parkinson’s disease: MRI analysis, nigrosome 1 and nigrosome 4 | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.1016/B978-0-12-815950-7.00017-5 | - |
dc.identifier.bibliographicCitation | Genetics, Neurology, Behavior, and Diet in Parkinson’s Disease: The Neuroscience of Parkinson’s Disease, Volume 2, pp.267 - 281 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85147601327 | - |
dc.citation.endPage | 281 | - |
dc.citation.startPage | 267 | - |
dc.citation.title | Genetics, Neurology, Behavior, and Diet in Parkinson’s Disease: The Neuroscience of Parkinson’s Disease, Volume 2 | - |
dc.contributor.affiliatedAuthor | Kim, Eung Yeop | - |
dc.contributor.affiliatedAuthor | Sung, Young Hee | - |
dc.type.docType | Book Chapter | - |
dc.subject.keywordAuthor | Dopamine transporter imaging | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.subject.keywordAuthor | Neuromelanin-sensitive imaging | - |
dc.subject.keywordAuthor | Nigrosome | - |
dc.subject.keywordAuthor | Quantitative susceptibility mapping | - |
dc.subject.keywordAuthor | Substantia nigra | - |
dc.description.journalRegisteredClass | scopus | - |
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