Clinical Trial to Reconfirm the Efficacy and Safety of Cefetamet Pivoxil Treatment in Sinusitis Patients: A Double-Blind, Randomized, Parallel Designed, Multicenter, Active Comparator Study (CASIS Study)
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Chan-Soon | - |
dc.contributor.author | Cho, Jin Hee | - |
dc.contributor.author | Lee, Heung-Man | - |
dc.contributor.author | Kim, Kyung-Su | - |
dc.contributor.author | Kim, Jin Kook | - |
dc.contributor.author | Kim, Dong-Young | - |
dc.contributor.author | Baek, Byoung Joon | - |
dc.contributor.author | Kim, Hyun Jun | - |
dc.contributor.author | Kim, Yong-Dae | - |
dc.contributor.author | Hwang, Chi Sang | - |
dc.contributor.author | Kim, Seon Tae | - |
dc.contributor.author | Cho, Seok Hyun | - |
dc.contributor.author | Kim, Yong Min | - |
dc.contributor.author | Lee, Seung Hoon | - |
dc.contributor.author | Jeong, Jin Hyeok | - |
dc.contributor.author | In, Seung Min | - |
dc.contributor.author | Kim, Byung Guk | - |
dc.date.accessioned | 2023-02-20T01:40:09Z | - |
dc.date.available | 2023-02-20T01:40:09Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2023-02 | - |
dc.identifier.issn | 0145-5613 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/86901 | - |
dc.description.abstract | Objective: To evaluate the clinical efficacy and safety of cefetamet pivoxil for the treatment of acute bacterial rhinosinusitis in Korean patients compared to treatment with cefdinir. Methods: A prospective, multicenter, randomized double-blind, comparative study was conducted by the Departments of Otorhinolaryngology-Head and Neck Surgery at 17 hospitals or universities in the Republic of Korea from March 2017 to April 2019. A total of 309 patients were screened and 249 patients participated in the study. Results: Treatment with cefetamet pivoxil for 2 weeks showed 82.4% clinical cure and improvement rates in patients with acute bacterial rhinosinusitis compared to 84.68% in those taking cefdinir for 2 weeks, showing that cefetamet pivoxil administered twice a day for 2 weeks was as effective as cefdinir 3 times a day for 2 weeks for the treatment of acute bacterial rhinosinusitis. The overall adverse reaction rates of both drugs were 10.56% in the cefetamet pivoxil group and 15.49% in the cefdinir group, without serious adverse events or drug reactions. Conclusions: Cefetamet pivoxil twice a day was as efficacious and safe as cefdinir 3 times a day for the treatment of acute bacterial rhinosinusitis, which suggested that cefetamet pivoxil may be a suitable alternative to cefdinir. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS INC | - |
dc.relation.isPartOf | ENT-EAR NOSE & THROAT JOURNAL | - |
dc.title | Clinical Trial to Reconfirm the Efficacy and Safety of Cefetamet Pivoxil Treatment in Sinusitis Patients: A Double-Blind, Randomized, Parallel Designed, Multicenter, Active Comparator Study (CASIS Study) | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000687815800001 | - |
dc.identifier.doi | 10.1177/01455613211036236 | - |
dc.identifier.bibliographicCitation | ENT-EAR NOSE & THROAT JOURNAL, v.102, no.2, pp.101 - 109 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85113431918 | - |
dc.citation.endPage | 109 | - |
dc.citation.startPage | 101 | - |
dc.citation.title | ENT-EAR NOSE & THROAT JOURNAL | - |
dc.citation.volume | 102 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Kim, Seon Tae | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | acute bacterial rhinosinusitis | - |
dc.subject.keywordAuthor | cefdinir | - |
dc.subject.keywordAuthor | cefetamet | - |
dc.subject.keywordAuthor | comparative study | - |
dc.subject.keywordAuthor | double-blinded method | - |
dc.subject.keywordPlus | STREPTOCOCCUS-PNEUMONIAE | - |
dc.subject.keywordPlus | PRACTICE GUIDELINE | - |
dc.subject.keywordPlus | ANTIMICROBIAL RESISTANCE | - |
dc.subject.keywordPlus | RHINOSINUSITIS | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.