Current and emerging applications of nanostructured metal organic frameworks in cancer-targeted theranostics
DC Field | Value | Language |
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dc.contributor.author | Lakshmi, Buddolla Anantha | - |
dc.contributor.author | Kim, Sanghyo | - |
dc.date.available | 2020-02-27T02:20:57Z | - |
dc.date.created | 2020-02-04 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 0928-4931 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/869 | - |
dc.description.abstract | Nanostructured metal-organic frameworks (N-MOFs) are crystalline coordination nanopolymers in which metals are conjugated with organic and inorganic linker molecules. At present, N-MOFs have attracted significant interest owing to their intrinsically high porosity and ultrahigh surface areas, which allow them to be loaded with a broad array of materials, including drug molecules. In addition, N-MOFs possess other unique properties, such as good mobility, high reactivity, outstanding stability, real-time intracellular pH sensitivity, photosensitization, and penetration ability, which make them suitable candidates as drug delivery carriers for cancer and other targeted therapies. The opportunity for using a diverse array of chemical building components in N-MOFs facilitates the formation of structures with preferred properties for targeted therapy. In this review, we focus on the synthesis, characterization and other potential applications of N-MOFs in targeted theranostic nanodrug for cancer therapy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.relation.isPartOf | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | - |
dc.subject | DRUG-DELIVERY SYSTEM | - |
dc.subject | MECHANOCHEMICAL SYNTHESIS | - |
dc.subject | ELECTROCHEMICAL SYNTHESIS | - |
dc.subject | SONOCHEMICAL SYNTHESIS | - |
dc.subject | MOF NANOPARTICLES | - |
dc.subject | SINGLET-OXYGEN | - |
dc.subject | PLATFORM | - |
dc.subject | THERAPY | - |
dc.subject | RESISTANT | - |
dc.subject | PH | - |
dc.title | Current and emerging applications of nanostructured metal organic frameworks in cancer-targeted theranostics | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000490044700003 | - |
dc.identifier.doi | 10.1016/j.msec.2019.110091 | - |
dc.identifier.bibliographicCitation | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, v.105 | - |
dc.identifier.scopusid | 2-s2.0-85070608169 | - |
dc.citation.title | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | - |
dc.citation.volume | 105 | - |
dc.contributor.affiliatedAuthor | Lakshmi, Buddolla Anantha | - |
dc.contributor.affiliatedAuthor | Kim, Sanghyo | - |
dc.type.docType | Review | - |
dc.subject.keywordAuthor | Nanostructured metal organic frameworks | - |
dc.subject.keywordAuthor | Cancer-targeted therapy | - |
dc.subject.keywordAuthor | Photosensitization | - |
dc.subject.keywordAuthor | Drug delivery | - |
dc.subject.keywordPlus | DRUG-DELIVERY SYSTEM | - |
dc.subject.keywordPlus | MECHANOCHEMICAL SYNTHESIS | - |
dc.subject.keywordPlus | ELECTROCHEMICAL SYNTHESIS | - |
dc.subject.keywordPlus | SONOCHEMICAL SYNTHESIS | - |
dc.subject.keywordPlus | MOF NANOPARTICLES | - |
dc.subject.keywordPlus | SINGLET-OXYGEN | - |
dc.subject.keywordPlus | PLATFORM | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | RESISTANT | - |
dc.subject.keywordPlus | PH | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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