Impact of donor hypertension on graft survival and function in living and deceased donor kidney transplantation: a nationwide prospective cohort study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Y.H. | - |
dc.contributor.author | Kim, J.S. | - |
dc.contributor.author | Song, S.H. | - |
dc.contributor.author | Song, S.H. | - |
dc.contributor.author | Shin, H.S. | - |
dc.contributor.author | Yang, J. | - |
dc.contributor.author | Ahn, C. | - |
dc.contributor.author | Jeong, K.H. | - |
dc.contributor.author | Hwang, H.S. | - |
dc.contributor.author | Kong, J.M. | - |
dc.contributor.author | Kwon, O.J. | - |
dc.contributor.author | Kim, D.G. | - |
dc.contributor.author | Jung, C.-W. | - |
dc.contributor.author | Kim, Y.H. | - |
dc.contributor.author | Kim, J.K. | - |
dc.contributor.author | Kim, C.-D. | - |
dc.contributor.author | Min, J.W. | - |
dc.contributor.author | Park, S.K. | - |
dc.contributor.author | Park, Y.H. | - |
dc.contributor.author | Berm, P.J. | - |
dc.contributor.author | Park, J.H. | - |
dc.contributor.author | Park, J.-W. | - |
dc.contributor.author | Ban, T.H. | - |
dc.contributor.author | Yang, C.W. | - |
dc.contributor.author | Yoon, H.E. | - |
dc.contributor.author | Lee, K.W. | - |
dc.contributor.author | Lee, D.R. | - |
dc.contributor.author | Lee, D.W. | - |
dc.contributor.author | Lee, S.Y. | - |
dc.contributor.author | Lee, S.-H. | - |
dc.contributor.author | Lee, S.H. | - |
dc.contributor.author | Lee, J.J. | - |
dc.contributor.author | Lee, J.P. | - |
dc.contributor.author | Lee, J.-H. | - |
dc.contributor.author | Jeon, J.S. | - |
dc.contributor.author | Jun, H. | - |
dc.contributor.author | Chung, K.Y. | - |
dc.contributor.author | Cho, H.R. | - |
dc.contributor.author | Ki, J.M. | - |
dc.contributor.author | Chae, D.-W. | - |
dc.contributor.author | Choi, S.J.N. | - |
dc.contributor.author | Han, D.J. | - |
dc.contributor.author | Han, S. | - |
dc.contributor.author | Huh, K.H. | - |
dc.date.accessioned | 2023-03-16T02:40:07Z | - |
dc.date.available | 2023-03-16T02:40:07Z | - |
dc.date.created | 2023-03-16 | - |
dc.date.issued | 2022-11 | - |
dc.identifier.issn | 0263-6352 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/87146 | - |
dc.description.abstract | Objectives: Hypertensive living donors are potential candidates to expand the kidney donor pool. However, the impact of donor hypertension on graft survival and function remains to be clarified. Methods: We analyzed 3907 kidney transplant recipients registered in a nationwide prospective cohort from 2014 to 2018. Patients were divided by donor types and the presence of donor hypertension. The primary and secondary outcome was the occurrence of death-censored graft failure and renal allograft function, respectively. Results: The prevalence of hypertension was 9.4% (258/2740) and 19.9% (232/1167) in living and deceased donors, respectively. During a median follow-up of 21.8months, death-censored graft survival rate was significantly worse in recipients of hypertensive living donors than in those of normotensive living donors (P¼0.008). In multivariable analysis, recipients of hypertensive living donors had a significantly increased risk of graft loss (adjusted hazard ratio 2.91; P¼0.009). The risk of allograft loss was not different between recipients of hypertensive living and normotensive deceased donors. Propensity score-matched analyses had consistent worse graft survival rate in recipients of hypertensive living donors compared to those of normotensive living donors (P¼0.027), while it was not different between recipients of hypertensive living and normotensive deceased donors. Hypertension in living donors had a significant negative impact on one-year graft function (adjusted unstandardized b -3.64; P¼0.011). Conclusions: Hypertensive living donor recipients have significantly higher risks of renal allograft loss than normotensive living donor recipients, and showed similar outcomes compared to recipients of normotensive deceased donors. © 2022 Wolters Kluwer Health, Inc. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Lippincott Williams and Wilkins | - |
dc.relation.isPartOf | Journal of Hypertension | - |
dc.title | Impact of donor hypertension on graft survival and function in living and deceased donor kidney transplantation: a nationwide prospective cohort study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000864723600014 | - |
dc.identifier.doi | 10.1097/HJH.0000000000003246 | - |
dc.identifier.bibliographicCitation | Journal of Hypertension, v.40, no.11, pp.2200 - 2209 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85139377780 | - |
dc.citation.endPage | 2209 | - |
dc.citation.startPage | 2200 | - |
dc.citation.title | Journal of Hypertension | - |
dc.citation.volume | 40 | - |
dc.citation.number | 11 | - |
dc.contributor.affiliatedAuthor | Park, Y.H. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | donor hypertension | - |
dc.subject.keywordAuthor | kidney transplantation | - |
dc.subject.keywordAuthor | renal allograft function | - |
dc.subject.keywordAuthor | renal allograft survival | - |
dc.subject.keywordPlus | BLOOD-PRESSURE | - |
dc.subject.keywordPlus | CYCLOSPORINE-A | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | TACROLIMUS | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.