A guide to the organ-on-a-chip
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Leung, Chak Ming | - |
dc.contributor.author | de Haan, Pim | - |
dc.contributor.author | Ronaldson-Bouchard, Kacey | - |
dc.contributor.author | Kim, Ge-Ah | - |
dc.contributor.author | Ko, Jihoon | - |
dc.contributor.author | Rho, Hoon Suk | - |
dc.contributor.author | Chen, Zhu | - |
dc.contributor.author | Habibovic, Pamela | - |
dc.contributor.author | Li Jeon, Noo | - |
dc.contributor.author | Takayama, Shuichi | - |
dc.contributor.author | Shuler, Michael L. | - |
dc.contributor.author | Vunjak-Novakovic, Gordana | - |
dc.contributor.author | Frey, Olivier | - |
dc.contributor.author | Verpoorte, Elisabeth | - |
dc.contributor.author | Toh, Yi-Chin | - |
dc.date.accessioned | 2023-03-27T06:41:53Z | - |
dc.date.available | 2023-03-27T06:41:53Z | - |
dc.date.created | 2023-03-27 | - |
dc.date.issued | 2022-05 | - |
dc.identifier.issn | 2662-8449 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/87296 | - |
dc.description.abstract | Organs-on-chips (OoCs) are systems containing engineered or natural miniature tissues grown inside microfluidic chips.To better mimic human physiology, the chips are designed to control cell microenvironments and maintain tissue-specific functions. Combining advances in tissue engineering and microfabrication, OoCs have gained interest as a next-generation experimental platform to investigate human pathophysiology and the effect of therapeutics in the body. There are as many examples of OoCs as there are applications, making it difficult for new researchers to understand what makes one OoC more suited to an application than another. This Primer is intended to give an introduction to the aspects of OoC that need to be considered when developing an application-specific OoC. The Primer covers guiding principles and considerations to design, fabricate and operate an OoC, as well as subsequent assaying techniques to extract biological information from OoC devices. Alongside this is a discussion of current and future applications of OoC technology, to inform design and operational decisions during the implementation of OoC systems. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGERNATURE | - |
dc.relation.isPartOf | NATURE REVIEWS METHODS PRIMERS | - |
dc.title | A guide to the organ-on-a-chip | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000888580100001 | - |
dc.identifier.doi | 10.1038/s43586-022-00118-6 | - |
dc.identifier.bibliographicCitation | NATURE REVIEWS METHODS PRIMERS, v.2, no.1 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85130220321 | - |
dc.citation.title | NATURE REVIEWS METHODS PRIMERS | - |
dc.citation.volume | 2 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Ko, Jihoon | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CELL-CULTURE ANALOG | - |
dc.subject.keywordPlus | IN-VITRO MODEL | - |
dc.subject.keywordPlus | MICROPHYSIOLOGICAL SYSTEMS MPS | - |
dc.subject.keywordPlus | FLUORESCENCE OPTICAL-DETECTION | - |
dc.subject.keywordPlus | BLOOD-BRAIN-BARRIER | - |
dc.subject.keywordPlus | ELECTRICAL-RESISTANCE | - |
dc.subject.keywordPlus | MICROFLUIDIC SYSTEMS | - |
dc.subject.keywordPlus | SHEAR-STRESS | - |
dc.subject.keywordPlus | LIVER-CELLS | - |
dc.subject.keywordPlus | NEURONAL DIFFERENTIATION | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.