Modulation of melanin synthesis by amaranthus spp. L seed extract in melan-a cells
DC Field | Value | Language |
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dc.contributor.author | Seo, J.O. | - |
dc.contributor.author | Do, M.H. | - |
dc.contributor.author | Lee, J.H. | - |
dc.contributor.author | Lee, T.H. | - |
dc.contributor.author | Wahedi, H.M. | - |
dc.contributor.author | Park, Y.U. | - |
dc.contributor.author | Kim, S.Y. | - |
dc.date.available | 2020-02-28T03:43:07Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2016-09 | - |
dc.identifier.issn | 1226-3907 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8764 | - |
dc.description.abstract | Anti-melanogenic effects of amaranth (AT), one of the key source of squalene, were investigated in melanocytes. Amaranth seed powder was extracted with water and melan-a cells were treated with various concentrations of AT. By using HPLC, content of myo-inositol, one of potential active components, was measured in the crude extract of AT.AT reduced the melanin content in melan-a melanocytes and down-regulated melanogenic enzyme activity such as tyrosinase, TRP-1 and TRP-2. By regulating melanogenic enzyme activity, AT may be a potential natural source for whitening agent. Myo-inositol was detected in AT by HPLC and may be one of the active compounds from AT involved in the regulation of anti-melanogenesis. In this study, we demonstrated that AT has anti-melanogenesis properties. This new function of amaranth may be useful in the development of new skin-whitening products and its value as food. © 2016, Korean Society of Pharmacognosy. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Society of Pharmacognosy | - |
dc.relation.isPartOf | Natural Product Sciences | - |
dc.title | Modulation of melanin synthesis by amaranthus spp. L seed extract in melan-a cells | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.20307/nps.2016.22.3.168 | - |
dc.identifier.bibliographicCitation | Natural Product Sciences, v.22, no.3, pp.168 - 174 | - |
dc.identifier.kciid | ART002147305 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84994850773 | - |
dc.citation.endPage | 174 | - |
dc.citation.startPage | 168 | - |
dc.citation.title | Natural Product Sciences | - |
dc.citation.volume | 22 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Seo, J.O. | - |
dc.contributor.affiliatedAuthor | Do, M.H. | - |
dc.contributor.affiliatedAuthor | Wahedi, H.M. | - |
dc.contributor.affiliatedAuthor | Park, Y.U. | - |
dc.contributor.affiliatedAuthor | Kim, S.Y. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Amaranth | - |
dc.subject.keywordAuthor | Melan-a cells | - |
dc.subject.keywordAuthor | Melanogenesis | - |
dc.subject.keywordAuthor | Myo-inositol | - |
dc.subject.keywordPlus | Amaranthus extract | - |
dc.subject.keywordPlus | depigmenting agent | - |
dc.subject.keywordPlus | dopachrome tautomerase | - |
dc.subject.keywordPlus | inositol | - |
dc.subject.keywordPlus | melanin | - |
dc.subject.keywordPlus | plant extract | - |
dc.subject.keywordPlus | tyrosinase related protein 1 | - |
dc.subject.keywordPlus | unclassified drug | - |
dc.subject.keywordPlus | Amaranthus | - |
dc.subject.keywordPlus | animal cell | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | cell viability | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | down regulation | - |
dc.subject.keywordPlus | enzyme activity | - |
dc.subject.keywordPlus | melanocyte | - |
dc.subject.keywordPlus | melanogenesis | - |
dc.subject.keywordPlus | mouse | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | plant seed | - |
dc.subject.keywordPlus | protein content | - |
dc.subject.keywordPlus | protein expression | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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