Bioresorbable, wireless, and battery-free system for electrotherapy and impedance sensing at wound sites
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Song, Joseph W. | - |
dc.contributor.author | Ryu, Hanjun | - |
dc.contributor.author | Bai, Wubin | - |
dc.contributor.author | Xie, Zhaoqian | - |
dc.contributor.author | Vazquez-Guardado, Abraham | - |
dc.contributor.author | Nandoliya, Khizar | - |
dc.contributor.author | Avila, Raudel | - |
dc.contributor.author | Lee, Geumbee | - |
dc.contributor.author | Song, Zhen | - |
dc.contributor.author | Kim, Jihye | - |
dc.contributor.author | Lee, Min-Kyu | - |
dc.contributor.author | Liu, Yugang | - |
dc.contributor.author | Kim, Mirae | - |
dc.contributor.author | Wang, Huifeng | - |
dc.contributor.author | Wu, Yixin | - |
dc.contributor.author | Yoon, Hong-Joon | - |
dc.contributor.author | Kwak, Sung Soo | - |
dc.contributor.author | Shin, Jaeho | - |
dc.contributor.author | Kwon, Kyeongha | - |
dc.contributor.author | Lu, Wei | - |
dc.contributor.author | Chen, Xuexian | - |
dc.contributor.author | Huang, Yonggang | - |
dc.contributor.author | Ameer, Guillermo A. | - |
dc.contributor.author | Rogers, John A. | - |
dc.date.accessioned | 2023-05-17T00:42:36Z | - |
dc.date.available | 2023-05-17T00:42:36Z | - |
dc.date.created | 2023-05-11 | - |
dc.date.issued | 2023-02 | - |
dc.identifier.issn | 2375-2548 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/87802 | - |
dc.description.abstract | Chronic wounds, particularly those associated with diabetes mellitus, represent a growing threat to public health, with additional notable economic impacts. Inflammation associated with these wounds leads to abnormalities in endogenous electrical signals that impede the migration of keratinocytes needed to support the healing process. This observation motivates the treatment of chronic wounds with electrical stimulation therapy, but practical engineering challenges, difficulties in removing stimulation hardware from the wound site, and absence of means to monitor the healing process create barriers to widespread clinical use. Here, we demonstrate a miniaturized wireless, battery-free bioresorbable electrotherapy system that overcomes these challenges. Studies based on a splinted diabetic mouse wound model confirm the efficacy for accelerated wound closure by guiding epithelial migration, modulating inflammation, and promoting vasculogenesis. Changes in the impedance provide means for tracking the healing process. The results demonstrate a simple and effective platform for wound site electrotherapy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER ASSOC ADVANCEMENT SCIENCE | - |
dc.relation.isPartOf | SCIENCE ADVANCES | - |
dc.title | Bioresorbable, wireless, and battery-free system for electrotherapy and impedance sensing at wound sites | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000949019100019 | - |
dc.identifier.doi | 10.1126/sciadv.ade4687 | - |
dc.identifier.bibliographicCitation | SCIENCE ADVANCES, v.9, no.8 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85148551109 | - |
dc.citation.title | SCIENCE ADVANCES | - |
dc.citation.volume | 9 | - |
dc.citation.number | 8 | - |
dc.contributor.affiliatedAuthor | Yoon, Hong-Joon | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | DIABETIC FOOT ULCERS | - |
dc.subject.keywordPlus | ELECTRICAL-STIMULATION | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | SKIN | - |
dc.subject.keywordPlus | HEAT | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.