Early onset of colorectal cancer in a 13-yearoldgirl with lynch syndrome
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ahn, D.H. | - |
dc.contributor.author | Rho, J.H. | - |
dc.contributor.author | Tchah, H. | - |
dc.contributor.author | Jeon, I.-S. | - |
dc.date.available | 2020-02-28T03:43:19Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1738-1061 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8782 | - |
dc.description.abstract | Lynch syndrome is the most common inherited colon cancer syndrome. Patients with Lynch syndromedevelop a range of cancers including colorectal cancer (CRC) and carry a mutation on one of themismatched repair (MMR) genes. Although CRC usually occurs after the fourth decade in patients withLynch syndrome harboring a heterozygous MMR gene mutation, it can occur in children with Lynchsyndrome who have a compound heterozygous or homozygous MMR gene mutation. We report a caseof CRC in a 13-year-old patient with Lynch syndrome and congenital heart disease. This patient had aheterozygous mutation in MLH1 (an MMR gene), but no compound MMR gene defects, and a K-RASsomatic mutation in the cancer cells. © 2016 by The Korean Pediatric Society. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Pediatric Society | - |
dc.relation.isPartOf | Korean Journal of Pediatrics | - |
dc.subject | fluorouracil | - |
dc.subject | folinic acid | - |
dc.subject | hemoglobin | - |
dc.subject | iron | - |
dc.subject | oxaliplatin | - |
dc.subject | abdominal mass | - |
dc.subject | adenocarcinoma | - |
dc.subject | adolescent | - |
dc.subject | Article | - |
dc.subject | biopsy | - |
dc.subject | bone marrow suppression | - |
dc.subject | cancer recurrence | - |
dc.subject | cancer staging | - |
dc.subject | case report | - |
dc.subject | colonoscopy | - |
dc.subject | colorectal cancer | - |
dc.subject | computer assisted tomography | - |
dc.subject | congenital heart disease | - |
dc.subject | endoscopy | - |
dc.subject | female | - |
dc.subject | gene mutation | - |
dc.subject | great vessels transposition | - |
dc.subject | Helicobacter infection | - |
dc.subject | hereditary nonpolyposis colorectal cancer | - |
dc.subject | histopathology | - |
dc.subject | human | - |
dc.subject | human tissue | - |
dc.subject | iron deficiency anemia | - |
dc.subject | iron therapy | - |
dc.subject | multiple cycle treatment | - |
dc.subject | polymerase chain reaction | - |
dc.subject | proctocolectomy | - |
dc.subject | weight reduction | - |
dc.title | Early onset of colorectal cancer in a 13-yearoldgirl with lynch syndrome | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.3345/kjp.2016.59.1.40 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pediatrics, v.59, no.1, pp.40 - 42 | - |
dc.identifier.kciid | ART002075679 | - |
dc.identifier.scopusid | 2-s2.0-84954486966 | - |
dc.citation.endPage | 42 | - |
dc.citation.startPage | 40 | - |
dc.citation.title | Korean Journal of Pediatrics | - |
dc.citation.volume | 59 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Ahn, D.H. | - |
dc.contributor.affiliatedAuthor | Rho, J.H. | - |
dc.contributor.affiliatedAuthor | Tchah, H. | - |
dc.contributor.affiliatedAuthor | Jeon, I.-S. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Colorectal neoplasms | - |
dc.subject.keywordAuthor | Lynch syndrome | - |
dc.subject.keywordAuthor | Mismatched repair genes | - |
dc.subject.keywordPlus | fluorouracil | - |
dc.subject.keywordPlus | folinic acid | - |
dc.subject.keywordPlus | hemoglobin | - |
dc.subject.keywordPlus | iron | - |
dc.subject.keywordPlus | oxaliplatin | - |
dc.subject.keywordPlus | abdominal mass | - |
dc.subject.keywordPlus | adenocarcinoma | - |
dc.subject.keywordPlus | adolescent | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | biopsy | - |
dc.subject.keywordPlus | bone marrow suppression | - |
dc.subject.keywordPlus | cancer recurrence | - |
dc.subject.keywordPlus | cancer staging | - |
dc.subject.keywordPlus | case report | - |
dc.subject.keywordPlus | colonoscopy | - |
dc.subject.keywordPlus | colorectal cancer | - |
dc.subject.keywordPlus | computer assisted tomography | - |
dc.subject.keywordPlus | congenital heart disease | - |
dc.subject.keywordPlus | endoscopy | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | gene mutation | - |
dc.subject.keywordPlus | great vessels transposition | - |
dc.subject.keywordPlus | Helicobacter infection | - |
dc.subject.keywordPlus | hereditary nonpolyposis colorectal cancer | - |
dc.subject.keywordPlus | histopathology | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | human tissue | - |
dc.subject.keywordPlus | iron deficiency anemia | - |
dc.subject.keywordPlus | iron therapy | - |
dc.subject.keywordPlus | multiple cycle treatment | - |
dc.subject.keywordPlus | polymerase chain reaction | - |
dc.subject.keywordPlus | proctocolectomy | - |
dc.subject.keywordPlus | weight reduction | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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