Epidemiologic and Clinical Outcomes of Pediatric Renal Tumors in Korea: A Retrospective Analysis of The Korean Pediatric Hematology and Oncology Group (KPHOG) Data
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dc.contributor.author | Koh, Kyung-Nam | - |
dc.contributor.author | Han, Jung Woo | - |
dc.contributor.author | Choi, Hyoung Soo | - |
dc.contributor.author | Kang, Hyoung Jin | - |
dc.contributor.author | Lee, Ji Won | - |
dc.contributor.author | Yoo, Keon Hee | - |
dc.contributor.author | Sung, Ki Woong | - |
dc.contributor.author | Koo, Hong Hoe | - |
dc.contributor.author | Hong, Kyung Taek | - |
dc.contributor.author | Choi, Jung Yoon | - |
dc.contributor.author | Kang, Sung Han | - |
dc.contributor.author | Kim, Hyery | - |
dc.contributor.author | Im, Ho Joon | - |
dc.contributor.author | Hahn, Seung Min | - |
dc.contributor.author | Lyu, Chuhl Joo | - |
dc.contributor.author | Baek, Hee-Jo | - |
dc.contributor.author | Kook, Hoon | - |
dc.contributor.author | Park, Kyung Mi | - |
dc.contributor.author | Yang, Eu Jeen | - |
dc.contributor.author | Lim, Young Tak | - |
dc.contributor.author | Kim, Seongkoo | - |
dc.contributor.author | Lee, Jae Wook | - |
dc.contributor.author | Chung, Nack-Gyun | - |
dc.contributor.author | Cho, Bin | - |
dc.contributor.author | Park, Meerim | - |
dc.contributor.author | Park, Hyeon Jin | - |
dc.contributor.author | Park, Byung-Kiu | - |
dc.contributor.author | Lee, Jun Ah | - |
dc.contributor.author | Park, Jun Eun | - |
dc.contributor.author | Kim, Soon Ki | - |
dc.contributor.author | Kim, Ji Yoon | - |
dc.contributor.author | Kim, Hyo Sun | - |
dc.contributor.author | Ma, Youngeun | - |
dc.contributor.author | Park, Kyung Duk | - |
dc.contributor.author | Park, Sang Kyu | - |
dc.contributor.author | Park, Eun Sil | - |
dc.contributor.author | Shim, Ye Jee | - |
dc.contributor.author | Yoo, Eun Sun | - |
dc.contributor.author | Ha Ryu, Kyung | - |
dc.contributor.author | Yoo, Jae Wo | - |
dc.contributor.author | Lim, Yeon Jung | - |
dc.contributor.author | Yoon, Hoi Soo | - |
dc.contributor.author | Lee, Mee Jeong | - |
dc.contributor.author | Lee, Jae Min | - |
dc.contributor.author | Jeon, In-Sang | - |
dc.contributor.author | Jung, Hye Lim | - |
dc.contributor.author | Chueh, Hee Won | - |
dc.contributor.author | Won, Seunghyun | - |
dc.date.accessioned | 2023-05-23T08:41:38Z | - |
dc.date.available | 2023-05-23T08:41:38Z | - |
dc.date.created | 2023-05-23 | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/87980 | - |
dc.description.abstract | Purpose Renal tumors account for approximately 7% of all childhood cancers. These include Wilms tumor (WT), clear cell sarcoma of the kidney (CCSK), malignant rhabdoid tumor of the kidney (MRTK), renal cell carcinoma (RCC), congenital mesoblastic nephroma (CMN) and other rare tumors. We investigated the epidemiology of pediatric renal tumors in Korea. Materials and Methods From January 2001 to December 2015, data of pediatric patients (0-18 years) newly-diagnosed with renal tumors at 26 hospitals were retrospectively analyzed.Results Among 439 patients (male, 240), the most common tumor was WT (n=342, 77.9%), followed by RCC (n=36, 8.2%), CCSK (n=24, 5.5%), MRTK (n=16, 3.6%), CMN (n=12, 2.7%), and others (n=9, 2.1%). Median age at diagnosis was 27.1 months (range, 0 to 225.5 months) and median follow-up duration was 88.5 months (range, 0 to 211.6 months). Overall, 32 patients died, of whom 17, 11, 1, and three died of relapse, progressive disease, second malignant neoplasm, and treatment-related mortality. Five-year overall survival and event-free survival were 97.2% and 84.8% in WT, 90.6% and 82.1% in RCC, 81.1% and 63.6% in CCSK, 60.3% and 56.2% in MRTK, and 100% and 91.7% in CMN, respectively (p < 0.001).Conclusion The pediatric renal tumor types in Korea are similar to those previously reported in other countries. WT accounted for a large proportion and survival was excellent. Non-Wilms renal tumors included a variety of tumors and showed inferior outcome, especially MRTK. Further efforts are necessary to optimize the treatment and analyze the genetic characteristics of pediatric renal tumors in Korea. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN CANCER ASSOCIATION | - |
dc.relation.isPartOf | CANCER RESEARCH AND TREATMENT | - |
dc.title | Epidemiologic and Clinical Outcomes of Pediatric Renal Tumors in Korea: A Retrospective Analysis of The Korean Pediatric Hematology and Oncology Group (KPHOG) Data | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000957087400025 | - |
dc.identifier.doi | 10.4143/crt.2022.073 | - |
dc.identifier.bibliographicCitation | CANCER RESEARCH AND TREATMENT, v.55, no.1, pp.279 - 290 | - |
dc.identifier.kciid | ART002923332 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85146364840 | - |
dc.citation.endPage | 290 | - |
dc.citation.startPage | 279 | - |
dc.citation.title | CANCER RESEARCH AND TREATMENT | - |
dc.citation.volume | 55 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Jeon, In-Sang | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Kidney neoplasms | - |
dc.subject.keywordAuthor | Child | - |
dc.subject.keywordAuthor | Epidemiology | - |
dc.subject.keywordPlus | WILMS-TUMOR | - |
dc.subject.keywordPlus | KIDNEY | - |
dc.subject.keywordPlus | PROTOCOLS | - |
dc.subject.keywordPlus | TURNOURS | - |
dc.subject.keywordPlus | BIOLOGY | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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