Drug_SNSMiner: standard pharmacovigilance pipeline for detection of adverse drug reaction using SNS dataopen access
- Authors
- Lee, Seunghee; Woo, Hyekyung; Lee, Chung Chun; Kim, Gyeongmin; Kim, Jong-Yeup; Lee, Suehyun
- Issue Date
- Mar-2023
- Publisher
- NATURE PORTFOLIO
- Citation
- Scientific Reports, v.13, no.1
- Journal Title
- Scientific Reports
- Volume
- 13
- Number
- 1
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/88538
- DOI
- 10.1038/s41598-023-28912-6
- ISSN
- 2045-2322
- Abstract
- As society continues to age, it is becoming increasingly important to monitor drug use in the elderly. Social media data have been used for monitoring adverse drug reactions. The aim of this study was to determine whether social network studies (SNS) are useful sources of drug side effects information. We propose a method for utilizing SNS data to plot the known side effects of geriatric drugs in a dosing map. We developed a lexicon of drug terms associated with side effects and mapped patterns from social media data. We confirmed that well-known side effects may be obtained by utilizing SNS data. Based on these results, we propose a pharmacovigilance pipeline that can be extended to unknown side effects. We propose the standard analysis pipeline Drug_SNSMiner for monitoring side effects using SNS data and evaluated it as a drug prescription platform for the elderly. We confirmed that side effects may be monitored from the consumer’s perspective based on SNS data using only drug information. SNS data were deemed good sources of information to determine ADRs and obtain other complementary data. We established that these learning data are invaluable for AI requiring the acquisition of ADR posts on efficacious drugs. © 2023, The Author(s).
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