Phenolic constituents from the twigs of Betula schmidtii collected in Goesan, Korea
- Authors
- Park, Kyoung Jin; Cha, Joon Min; Subedi, Lalita; Kim, Sun Yeou; Lee, Kang Ro
- Issue Date
- Nov-2019
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- Betula schmidtii Regel; Betulaceae; Phenolic derivatives; Anti-inflammatory activity
- Citation
- PHYTOCHEMISTRY, v.167
- Journal Title
- PHYTOCHEMISTRY
- Volume
- 167
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/888
- DOI
- 10.1016/j.phytochem.2019.112085
- ISSN
- 0031-9422
- Abstract
- Six undescribed phenolic derivatives along with thirty two known compounds were isolated from the twigs of Betula schmidtii. The chemical structures were characterized through extensive spectroscopic analysis and chemical methods. All known compounds were first isolated in this plant. The anti-inflammatory effect of the isolates was tested by measuring nitric oxide production in lipopolysaccharide-activated BV-2 cells. Isotachioside, 4-allyl-2-hydrophenyl 1-O-beta-D-apiosyl-(1 (R) 6)-beta-D-glucopyranoside, genistein 5-O-beta-D-glucoside, and prunetinoside showed a slight potency to lower the NO production against LPS-activated microglia with IC50 values of 23.9, 25.3, 28.8, and 34.0 mu M, respectively.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 약학대학 > 약학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/888)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.