Enhancement of Functional Surface and Molecular Dynamics at Pt-rGO by Spacer 1, 6-Hexanediamine for Precise Detection of Biomolecues: Uric acid as a Specimen

Abstract

The enhancement of functional surface and molecular migration through reduced graphene oxide (rGO) with consequent detection of low concentration uric acid (UA) is presented. We observed excellent molecular permission in an organic-inorganic hybrid, where 1,6-Hexanediamine (HA) was incorporated at rGO-platinum (Pt) matrices to obtain HA-rGO-Pt. The rGO, Pt and HA precursor played the role of conductive template, electro catalyst, and spacer group. As sensing probe with active surface area of 0.0316 cm2 on glassy carbon electrode, the material afforded precise uric acid (UA) detection with linear dynamic range (LDR), and sensitivity as 0.1 nM∼0.1 mM UA, and 24.2089 µAµM-1cm-2. The signal to noise ratio was 3, and the lower limit of detection (LOD) was 39.22±1.96 pM. The high sensitivity and rapid detection of UA was possible due to the improved hydronium ion permittivity (∼10−5-10−4 Scm−1), and moderate electron conductivity. This strategy of widening molecular migration track might be considered as a facile way to adopt graphene based hybrids for various applications including sensing and catalysis.