Factors for achieving target serum uric acid levels after initiating urate-lowering therapy in patients with gout: results from the ULTRA registry
DC Field | Value | Language |
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dc.contributor.author | Do, Hyunsue | - |
dc.contributor.author | Choi, Hyo Jin | - |
dc.contributor.author | Choi, Byoongyong | - |
dc.contributor.author | Son, Chang-Nam | - |
dc.contributor.author | Kim, Sang-Hyon | - |
dc.contributor.author | Choi, Se Rim | - |
dc.contributor.author | Kim, Ji Hyoun | - |
dc.contributor.author | Kim, Min Jung | - |
dc.contributor.author | Shin, Kichul | - |
dc.contributor.author | Kim, Hyun-Ok | - |
dc.contributor.author | Song, Ran | - |
dc.contributor.author | Lee, Sung Won | - |
dc.contributor.author | Ahn, Joong Kyong | - |
dc.contributor.author | Lee, Seung-Geun | - |
dc.contributor.author | Lee, Chang Hoon | - |
dc.contributor.author | Son, Kyeong Min | - |
dc.contributor.author | Moon, Ki Won | - |
dc.date.accessioned | 2024-01-17T00:01:25Z | - |
dc.date.available | 2024-01-17T00:01:25Z | - |
dc.date.issued | 2023-11 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90144 | - |
dc.description.abstract | Achieving target serum uric acid (SUA) levels is important in gout management. Guidelines recommend lowering SUA levels to < 6 mg/dL; however, many patients fail to reach this target, even with uric acid-lowering therapy (ULT). This study investigated clinical characteristics of target SUA achievers among Korean patients with gout. This study used data from the ULTRA registry, a nationwide inception cohort established in September 2021 that enrolls patients with gout who initiate ULT. Demographic, clinical, and laboratory data were collected at baseline; the 6-month follow-up. Patients were divided into two groups: target achievers (SUA level < 6 mg/dL at 6 months) and non-achievers. The mean participant (N = 117) age was 56.1 years, and 88.0% were male. At 6 months, 83 patients (70.9%) reached target SUA levels. Target achievers had better drug adherence (>= 80%) to ULT (97.6% vs. 76.5%; p < 0.01) than non-achievers. Target non-achievers had a higher percentage of a family history of gout (32.4% vs. 10.8%; p < 0.01) and less antihypertensive agent use (38.2% vs. 59.0%; p = 0.03) than target achievers. Multivariate regression analysis revealed that good adherence to ULT, the absence of a family history of gout, and antihypertensive agent use were key factors associated with achieving target SUA levels at 6 months. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | Factors for achieving target serum uric acid levels after initiating urate-lowering therapy in patients with gout: results from the ULTRA registry | - |
dc.type | Article | - |
dc.identifier.wosid | 001124641700040 | - |
dc.identifier.doi | 10.1038/s41598-023-47790-6 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.13, no.1 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85177473874 | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 13 | - |
dc.citation.number | 1 | - |
dc.type.docType | Article | - |
dc.publisher.location | 독일 | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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