The Usefulness of 18F-FDG PET to Differentiate Subtypes of Dementia: The Systematic Review and Meta-Analysis
DC Field | Value | Language |
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dc.contributor.author | Na, Seunghee | - |
dc.contributor.author | Kang, Dong Woo | - |
dc.contributor.author | Kim, Geon Ha | - |
dc.contributor.author | Kim, Ko Woon | - |
dc.contributor.author | Kim, Yeshin | - |
dc.contributor.author | Kim, Hee-Jin | - |
dc.contributor.author | Park, Kee Hyung | - |
dc.contributor.author | Park, Young Ho | - |
dc.contributor.author | Byeon, Gihwan | - |
dc.contributor.author | Suh, Jeewon | - |
dc.contributor.author | Shin, Joon Hyun | - |
dc.contributor.author | Shim, YongSoo | - |
dc.contributor.author | Yang, YoungSoon | - |
dc.contributor.author | Um, Yoo Hyun | - |
dc.contributor.author | Oh, Seong-il | - |
dc.contributor.author | Wang, Sheng-Min | - |
dc.contributor.author | Yoon, Bora | - |
dc.contributor.author | Yoon, Hai-Jeon | - |
dc.contributor.author | Lee, Sun Min | - |
dc.contributor.author | Lee, Juyoun | - |
dc.contributor.author | Lee, Jin San | - |
dc.contributor.author | Rhee, Hak Young | - |
dc.contributor.author | Lim, Jae-Sung | - |
dc.contributor.author | Jung, Young Hee | - |
dc.contributor.author | Chin, Juhee | - |
dc.contributor.author | Hong, Yun Jeong | - |
dc.contributor.author | Jang, Hyemin | - |
dc.contributor.author | Choi, Hongyoon | - |
dc.contributor.author | Choi, Miyoung | - |
dc.contributor.author | Jang, Jae-Won | - |
dc.date.accessioned | 2024-02-09T02:00:16Z | - |
dc.date.available | 2024-02-09T02:00:16Z | - |
dc.date.issued | 2024-01 | - |
dc.identifier.issn | 1738-1495 | - |
dc.identifier.issn | 2384-0757 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90346 | - |
dc.description.abstract | Background and Purpose: Dementia subtypes, including Alzheimer’s dementia (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD), pose diagnostic challenges. This review examines the effectiveness of 18F-Fluorodeoxyglucose Positron Emission Tomography (18F-FDG PET) in differentiating these subtypes for precise treatment and management. Methods: A systematic review following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines was conducted using databases like PubMed and Embase to identify studies on the diagnostic utility of 18F-FDG PET in dementia. The search included studies up to November 16, 2022, focusing on peer-reviewed journals and applying the gold-standard clinical diagnosis for dementia subtypes. Results: From 12,815 articles, 14 were selected for final analysis. For AD versus FTD, the sensitivity was 0.96 (95% confidence interval [CI], 0.88–0.98) and specificity was 0.84 (95% CI, 0.70–0.92). In the case of AD versus DLB, 18F-FDG PET showed a sensitivity of 0.93 (95% CI 0.88-0.98) and specificity of 0.92 (95% CI, 0.70–0.92). Lastly, when differentiating AD from non-AD dementias, the sensitivity was 0.86 (95% CI, 0.80–0.91) and the specificity was 0.88 (95% CI, 0.80–0.91). The studies mostly used case-control designs with visual and quantitative assessments. Conclusions: 18F-FDG PET exhibits high sensitivity and specificity in differentiating dementia subtypes, particularly AD, FTD, and DLB. This method, while not a standalone diagnostic tool, significantly enhances diagnostic accuracy in uncertain cases, complementing clinical assessments and structural imaging. | - |
dc.format.extent | 13 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한치매학회 | - |
dc.title | The Usefulness of 18F-FDG PET to Differentiate Subtypes of Dementia: The Systematic Review and Meta-Analysis | - |
dc.type | Article | - |
dc.identifier.doi | 10.12779/dnd.2024.23.1.54 | - |
dc.identifier.bibliographicCitation | Dementia and Neurocognitive Disorders(대한치매학회지), v.23, no.1, pp 54 - 66 | - |
dc.identifier.kciid | ART003050346 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 66 | - |
dc.citation.startPage | 54 | - |
dc.citation.title | Dementia and Neurocognitive Disorders(대한치매학회지) | - |
dc.citation.volume | 23 | - |
dc.citation.number | 1 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Fluorodeoxyglucose F18 | - |
dc.subject.keywordAuthor | Positron Emission Tomography Computed Tomography | - |
dc.subject.keywordAuthor | Dementia | - |
dc.subject.keywordAuthor | Meta-Analysis | - |
dc.subject.keywordAuthor | Alzheimer’s Disease | - |
dc.subject.keywordAuthor | Frontotemporal Dementia | - |
dc.subject.keywordAuthor | Lewy Body Disease | - |
dc.description.journalRegisteredClass | kci | - |
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