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Clinical safety and effectiveness of the Genoss drug-eluting stent in real-world clinical practice

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dc.contributor.authorYoun, Young Jin-
dc.contributor.authorLee, Jun-Won-
dc.contributor.authorAhn, Sung Gyun-
dc.contributor.authorLee, Seung-Hwan-
dc.contributor.authorYoon, Junghan-
dc.contributor.authorPark, Jae Hyoung-
dc.contributor.authorYoo, Sang-Yong-
dc.contributor.authorKang, Woong Chol-
dc.contributor.authorLee, Nam Ho-
dc.contributor.authorKwon, Ki Hwan-
dc.contributor.authorDoh, Joon Hyung-
dc.contributor.authorLim, Sang-Wook-
dc.contributor.authorJang, Yang Soo-
dc.contributor.authorJeon, Dong Woon-
dc.contributor.authorHeo, Jung Ho-
dc.contributor.authorChoi, Woong Gil-
dc.contributor.authorCho, Sungsoo-
dc.contributor.authorLee, Bong-Ki-
dc.contributor.authorJeong, Hyonju-
dc.contributor.authorHong, Bum-Kee-
dc.contributor.authorChoi, Hyun-Hee-
dc.date.accessioned2024-02-14T00:00:34Z-
dc.date.available2024-02-14T00:00:34Z-
dc.date.issued2023-09-
dc.identifier.issn1226-3303-
dc.identifier.issn2005-6648-
dc.identifier.urihttps://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90395-
dc.description.abstractBackground/Aims: The Genoss DESTM is a novel, biodegradable, polymer-coated, sirolimus-eluting stent with a cobalt-chromium stent platform and thin strut. Although the safety and effectiveness of this stent have been previously investigated, real-world clinical outcomes data are lacking. Therefore, the aim of this prospective, multicenter trial was to evaluate the clinical safety and effectiveness of the Genoss DESTM in all-comer patients undergoing percutaneous coronary intervention.Methods: The Genoss DES registry is a prospective, single-arm, observational trial for evaluation of clinical outcomes after Genoss DESTM implantation in all-comer patients undergoing percutaneous coronary intervention from 17 sites in South Korea. The primary endpoint was a device-oriented composite outcome of cardiac death, target vessel-related myocardial infarction (MI), and clinically driven target lesion revascularization (TLR) at 12 months.Results: A total of 1,999 patients (66.4 & PLUSMN; 11.1 years of age; 72.8% male) were analyzed. At baseline, 62.8% and 36.7% of patients had hypertension and diabetes, respectively. The implanted stent number, diameter, and length per patient were 1.5 & PLUSMN; 0.8, 3.1 & PLUSMN; 0.5 mm, and 37.0 & PLUSMN; 25.0 mm, respectively. The primary endpoint occurred in 1.8% patients, with a cardiac death rate of 1.1%, target vessel-related MI rate of 0.2%, and clinically driven TLR rate of 0.8%.Conclusions: In this real-world registry, the Genoss DESTM demonstrated excellent safety and effectiveness at 12 months among all-comer patients undergoing percutaneous coronary intervention. These findings suggest that the Genoss DESTM may be a viable treatment option for patients with coronary artery disease.-
dc.format.extent9-
dc.language영어-
dc.language.isoENG-
dc.publisherKOREAN ASSOC INTERNAL MEDICINE-
dc.titleClinical safety and effectiveness of the Genoss drug-eluting stent in real-world clinical practice-
dc.typeArticle-
dc.identifier.wosid001150514800011-
dc.identifier.doi10.3904/kjim.2023.129-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF INTERNAL MEDICINE, v.38, no.5, pp 683 - 691-
dc.identifier.kciidART002992205-
dc.description.isOpenAccessY-
dc.identifier.scopusid2-s2.0-85170294121-
dc.citation.endPage691-
dc.citation.startPage683-
dc.citation.titleKOREAN JOURNAL OF INTERNAL MEDICINE-
dc.citation.volume38-
dc.citation.number5-
dc.type.docTypeArticle-
dc.publisher.location대한민국-
dc.subject.keywordAuthorDrug-eluting stents-
dc.subject.keywordAuthorPercutaneous coronary intervention-
dc.subject.keywordAuthorProspective studies-
dc.subject.keywordAuthorRegistries-
dc.subject.keywordPlusCORONARY-ARTERY-DISEASE-
dc.subject.keywordPlusMULTICENTER-
dc.subject.keywordPlusOUTCOMES-
dc.subject.keywordPlusTRIALS-
dc.relation.journalResearchAreaGeneral & Internal Medicine-
dc.relation.journalWebOfScienceCategoryMedicine, General & Internal-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
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