Clinical safety and effectiveness of the Genoss drug-eluting stent in real-world clinical practice
DC Field | Value | Language |
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dc.contributor.author | Youn, Young Jin | - |
dc.contributor.author | Lee, Jun-Won | - |
dc.contributor.author | Ahn, Sung Gyun | - |
dc.contributor.author | Lee, Seung-Hwan | - |
dc.contributor.author | Yoon, Junghan | - |
dc.contributor.author | Park, Jae Hyoung | - |
dc.contributor.author | Yoo, Sang-Yong | - |
dc.contributor.author | Kang, Woong Chol | - |
dc.contributor.author | Lee, Nam Ho | - |
dc.contributor.author | Kwon, Ki Hwan | - |
dc.contributor.author | Doh, Joon Hyung | - |
dc.contributor.author | Lim, Sang-Wook | - |
dc.contributor.author | Jang, Yang Soo | - |
dc.contributor.author | Jeon, Dong Woon | - |
dc.contributor.author | Heo, Jung Ho | - |
dc.contributor.author | Choi, Woong Gil | - |
dc.contributor.author | Cho, Sungsoo | - |
dc.contributor.author | Lee, Bong-Ki | - |
dc.contributor.author | Jeong, Hyonju | - |
dc.contributor.author | Hong, Bum-Kee | - |
dc.contributor.author | Choi, Hyun-Hee | - |
dc.date.accessioned | 2024-02-14T00:00:34Z | - |
dc.date.available | 2024-02-14T00:00:34Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.issn | 2005-6648 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/90395 | - |
dc.description.abstract | Background/Aims: The Genoss DESTM is a novel, biodegradable, polymer-coated, sirolimus-eluting stent with a cobalt-chromium stent platform and thin strut. Although the safety and effectiveness of this stent have been previously investigated, real-world clinical outcomes data are lacking. Therefore, the aim of this prospective, multicenter trial was to evaluate the clinical safety and effectiveness of the Genoss DESTM in all-comer patients undergoing percutaneous coronary intervention.Methods: The Genoss DES registry is a prospective, single-arm, observational trial for evaluation of clinical outcomes after Genoss DESTM implantation in all-comer patients undergoing percutaneous coronary intervention from 17 sites in South Korea. The primary endpoint was a device-oriented composite outcome of cardiac death, target vessel-related myocardial infarction (MI), and clinically driven target lesion revascularization (TLR) at 12 months.Results: A total of 1,999 patients (66.4 & PLUSMN; 11.1 years of age; 72.8% male) were analyzed. At baseline, 62.8% and 36.7% of patients had hypertension and diabetes, respectively. The implanted stent number, diameter, and length per patient were 1.5 & PLUSMN; 0.8, 3.1 & PLUSMN; 0.5 mm, and 37.0 & PLUSMN; 25.0 mm, respectively. The primary endpoint occurred in 1.8% patients, with a cardiac death rate of 1.1%, target vessel-related MI rate of 0.2%, and clinically driven TLR rate of 0.8%.Conclusions: In this real-world registry, the Genoss DESTM demonstrated excellent safety and effectiveness at 12 months among all-comer patients undergoing percutaneous coronary intervention. These findings suggest that the Genoss DESTM may be a viable treatment option for patients with coronary artery disease. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.title | Clinical safety and effectiveness of the Genoss drug-eluting stent in real-world clinical practice | - |
dc.type | Article | - |
dc.identifier.wosid | 001150514800011 | - |
dc.identifier.doi | 10.3904/kjim.2023.129 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.38, no.5, pp 683 - 691 | - |
dc.identifier.kciid | ART002992205 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85170294121 | - |
dc.citation.endPage | 691 | - |
dc.citation.startPage | 683 | - |
dc.citation.title | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 38 | - |
dc.citation.number | 5 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Drug-eluting stents | - |
dc.subject.keywordAuthor | Percutaneous coronary intervention | - |
dc.subject.keywordAuthor | Prospective studies | - |
dc.subject.keywordAuthor | Registries | - |
dc.subject.keywordPlus | CORONARY-ARTERY-DISEASE | - |
dc.subject.keywordPlus | MULTICENTER | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | TRIALS | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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