Chemical Inhibition of Cell Recovery after Irradiation with Sparsely and Densely Ionizing Radiation
DC Field | Value | Language |
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dc.contributor.author | Ekaterina S. Evstratova | - |
dc.contributor.author | 김진홍 | - |
dc.contributor.author | 임영기 | - |
dc.contributor.author | 김진규 | - |
dc.contributor.author | Vladislav G. Petin | - |
dc.date.available | 2020-02-28T04:42:32Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1976-2402 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/9056 | - |
dc.description.abstract | The dependence of cell survival on exposure dose and the duration of the liquidholding recovery (LHR) was obtained for diploid yeast cells irradiated with ionizing radiation of different linear energy transfer (LET) and recovering from radiation damage without and with various concentrations of cisplatin - the most widely used anticancer drug. The ability of yeast cells to recover from radiation damage was less effective after cell exposure to high-LET radiation, when cells were irradiated without drug. The increase in cisplatin concentration resulted in the disappearance of this difference whereas the fraction of irreversible damage was permanently enlarged independently of radiation quality. The probability of cell recovery was shown to be constant for various conditions of irradiation and recovery. A new mechanism of cisplatin action was suggested according with which the inhibition of cell recovery after exposure to ionizing radiations was completely explained by the production of irreversible damage. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | (사)한국방사선산업학회 | - |
dc.relation.isPartOf | 방사선산업학회지 | - |
dc.title | Chemical Inhibition of Cell Recovery after Irradiation with Sparsely and Densely Ionizing Radiation | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 방사선산업학회지, v.10, no.4, pp.199 - 204 | - |
dc.identifier.kciid | ART002190870 | - |
dc.citation.endPage | 204 | - |
dc.citation.startPage | 199 | - |
dc.citation.title | 방사선산업학회지 | - |
dc.citation.volume | 10 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | 임영기 | - |
dc.subject.keywordAuthor | Yeast cells | - |
dc.subject.keywordAuthor | Gamma-rays | - |
dc.subject.keywordAuthor | Alpha-particles | - |
dc.subject.keywordAuthor | Chemical inhibitor | - |
dc.subject.keywordAuthor | Cell recovery | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
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